CAJ | 학술논문

儿茶素类化合物是一类具有多种生理活性的多酚类抗氧化剂．本文综述了国内外利用分子修饰法制备脂溶性儿茶素类化合物的进展。化学法主要利用酰氯在化学催化剂作用下反应制备脂溶性儿茶素．但是酰化反应发生的位点有所不同．总的来说酰基供体碳链长度一般大于等于8；酶法主要利用脂肪酶使脂肪酸或脂肪酸酯通过直接酯化或酯交换反应制备脂溶性儿茶素．在儿茶素及其化合物上键合烷基．由此提高了儿茶素类化合物在油脂体系中的溶解度，拓展了其应用领域。
인다소류화합물시일류구유다충생리활성적다분류항양화제．본문종술료국내외이용분자수식법제비지용성인다소류화합물적진전。화학법주요이용선록재화학최화제작용하반응제비지용성인다소．단시선화반응발생적위점유소불동．총적래설선기공체탄련장도일반대우등우8；매법주요이용지방매사지방산혹지방산지통과직접지화혹지교환반응제비지용성인다소．재인다소급기화합물상건합완기．유차제고료인다소류화합물재유지체계중적용해도，탁전료기응용영역。
Catechin compounds is one kind of polyphenol antioxidant that possess a great physiological aetivties. In this paper, progress of lipid-soluble catechins＇ preparation that use molecules modification were reviewed. Chemical method is mainly using carbonyl chlorides and catechin compounds in reaction under the role of chemical catalyst to prepare lipid-soluble catechins. But acylation reaction happened at different locus. The carbon chain length of acyl donors generally is more than 8. Enzymatic modification is mainly using fatty acid or fatty acid ester with catechins under the role of lipase, then direct esterification or ester exchange happened to get lipid-soluble catechins. Alkyl is bonded in catchin compounds, thus solubility in oil system of the catechin compounds is raising, and expand the application fields.