精细与专用化学品
精細與專用化學品
정세여전용화학품
FINE AND SPECIALTY CHEMICALS
2012年
7期
37-39
,共3页
孙婷婷%黄斌%周素文%张宏斌%戴念维%丁木生%蒋立建
孫婷婷%黃斌%週素文%張宏斌%戴唸維%丁木生%蔣立建
손정정%황빈%주소문%장굉빈%대념유%정목생%장립건
咔唑%Ullmann反应%3,6-二-(3,6-二叔丁基咔唑基)-咔唑
咔唑%Ullmann反應%3,6-二-(3,6-二叔丁基咔唑基)-咔唑
잡서%Ullmann반응%3,6-이-(3,6-이숙정기잡서기)-잡서
carbazole%Ullmann reaction%3,136-di(tert-butylcarbazolyl) carbazole
以咔唑为主要原料,经烃化、碘代、磺酰化、Ullmann反应和水解反应合成了3,6-二（3,6-二叔丁基咔唑基）-咔唑,五步反应总收率为50.3%,中间体及产品进行了1 HNMR检测。该合成工艺具有路线简单、操作方便、产率高等优点,适合大批量制备。
以咔唑為主要原料,經烴化、碘代、磺酰化、Ullmann反應和水解反應閤成瞭3,6-二（3,6-二叔丁基咔唑基）-咔唑,五步反應總收率為50.3%,中間體及產品進行瞭1 HNMR檢測。該閤成工藝具有路線簡單、操作方便、產率高等優點,適閤大批量製備。
이잡서위주요원료,경경화、전대、광선화、Ullmann반응화수해반응합성료3,6-이（3,6-이숙정기잡서기）-잡서,오보반응총수솔위50.3%,중간체급산품진행료1 HNMR검측。해합성공예구유로선간단、조작방편、산솔고등우점,괄합대비량제비。
3,6-Di（tert-butylcarbazolyl）carbazole was synthesized by using carbazole as the starting material via alkylation, iodination, sulfonylation, Ullmann reaction and hydrolysis reaction. The total yield of five steps was 50.3%. Structure of the product and intermediate was confirmed by i HNMR and MS. This method has many advantages, such as easy operation and high yield, which can he feasible to large scale preparation.
