CAJ | 학술논문

目的：促进绿色化学的发展。方法用α-吡咯烷酮(2)和对甲氧基苯甲酸(4)一步合成茴拉西坦(1)。结果产物结构经元素分析及红外光谱确认，含量及有关物质经高效液相色谱法检测合格。结论报道的合成方法原子利用率高、污染小，是绿色的合成方法。
목적：촉진록색화학적발전。방법용α-필각완동(2)화대갑양기분갑산(4)일보합성회랍서탄(1)。결과산물결구경원소분석급홍외광보학인，함량급유관물질경고효액상색보법검측합격。결론보도적합성방법원자이용솔고、오염소，시록색적합성방법。
Objective To promote the development of green chemistry.Methods Aniracetam (1)was synthesized fromα-pyrrolidone (2)and p-methoxy-benzoic acid(4)via only one step.Results The structure of the product was confirmed by elemental analysis and infrared spectrometry.The content and related substances of the product was detected by high performance liquid chromatog-raphy.Conclusion This synthetic method was featured with a high atom utilization and lower pollution,which could be considered as a green synthetic method.