CAJ | 학술논문

目的：系统评价三黄膏治疗急性软组织损伤的临床疗效。方法：计算机检索中国生物医学文献数据库(CBM)、维普中文科技期刊数据库(VIP)、中国期刊全文数据库(CNKI)，同时手工检索相关杂志专业资料；时限为1979年1月至2012年9月；制定文献纳入标准，由2位评价员分别独立筛选提取资料。应用Cochrane协作网提供的Revman 5.0进行Meta分析。结果：共纳入6篇文献，809例患者。Meta分析结果显示三黄膏治疗急性软组织损伤的临床疗效[OR=5.69，95%CI(3.00～10.78)]优于对照组，2组相比差异有统计学意义。结论：三黄膏可显著减轻疼痛、肿胀等炎症反应，在提高临床疗效方面可能优于对照组，但由于纳入研究质量低且样本量小，尚需多中心高质量的随机对照试验进一步证明。
목적：계통평개삼황고치료급성연조직손상적림상료효。방법：계산궤검색중국생물의학문헌수거고(CBM)、유보중문과기기간수거고(VIP)、중국기간전문수거고(CNKI)，동시수공검색상관잡지전업자료；시한위1979년1월지2012년9월；제정문헌납입표준，유2위평개원분별독립사선제취자료。응용Cochrane협작망제공적Revman 5.0진행Meta분석。결과：공납입6편문헌，809례환자。Meta분석결과현시삼황고치료급성연조직손상적림상료효[OR=5.69，95%CI(3.00～10.78)]우우대조조，2조상비차이유통계학의의。결론：삼황고가현저감경동통、종창등염증반응，재제고림상료효방면가능우우대조조，단유우납입연구질량저차양본량소，상수다중심고질량적수궤대조시험진일보증명。
Objective:To evaluate clinical effects of SanHuang ointment in treating acute soft tissue injury sys-tematically. Methods:CBM, VIP and CNKI were searched on computers, and relevant journals searched manually from January, 1979 to September, 2012;the included criteria were established, the information was screened and ab-stracted by two evaluators independently and respectively. Meta analysis was performed with Revman5.0 offered by Cochrane Collaboration. Results: Six pieces of articles were included and altogether 809 persons. The results of Meta analysis showed that clinical effect of SanHuang ointment in treating acute soft tissue injury [OR=5.69, 95%CI (3.00~10.78)] was superior to that of the control group, and the difference had statistical meaning between both groups. Conclusion:SanHuang ointment could relieve inflammatory reactions such as the pain, the swelling and oth-ers significantly, since the included study was in low quality and with small sample size, multi-centered and high quality randomized controlled test needs to be further proved.