湖北民族学院学报(自然科学版)
湖北民族學院學報(自然科學版)
호북민족학원학보(자연과학판)
JOURNAL OF HUBEI INSTITUTE FOR NATIONALITIES(NATURAL SCIENCE EDITION)
2014年
1期
12-15
,共4页
淫羊藿%活性成分%变异%药材来源%中药现代化
淫羊藿%活性成分%變異%藥材來源%中藥現代化
음양곽%활성성분%변이%약재래원%중약현대화
Epimedium%active components%variation%drug source%TCM standardization
对我国部分市售淫羊藿药材的主要活性成分进行抽样检测证明:不同地区淫羊藿药材成分含量差异极显著,淫羊藿苷、朝藿定A、B、C四种成分总含量在1.49%~6.96%之间,总黄酮变异在4.15%~9.66%之间.部分药材四种黄酮总含量和总黄酮含量低于药典标准.在不同地区采集的药典规定的五种淫羊藿药材在成分组成和含量方面差异极显著,四种黄酮总含量变异在2.08%~5.38%之间;以巫山淫羊藿为例,不同产地和同一产地的巫山淫羊藿药材个体间在四种黄酮组成上有明显差异,在四种黄酮总含量和总黄酮含量上差异极显著.因此,淫羊藿药材标准化应该从以下几个方面研究:①对野生资源进行系统地调查和评估,筛选活性成分相关的优良遗传资源;②进行种质改良,培育优良新品种,推进中药材品种标准化;③研究适宜的栽培条件和栽培技术,为GAP基地建设和中药质量标准化提供物质基础和技术基础.
對我國部分市售淫羊藿藥材的主要活性成分進行抽樣檢測證明:不同地區淫羊藿藥材成分含量差異極顯著,淫羊藿苷、朝藿定A、B、C四種成分總含量在1.49%~6.96%之間,總黃酮變異在4.15%~9.66%之間.部分藥材四種黃酮總含量和總黃酮含量低于藥典標準.在不同地區採集的藥典規定的五種淫羊藿藥材在成分組成和含量方麵差異極顯著,四種黃酮總含量變異在2.08%~5.38%之間;以巫山淫羊藿為例,不同產地和同一產地的巫山淫羊藿藥材箇體間在四種黃酮組成上有明顯差異,在四種黃酮總含量和總黃酮含量上差異極顯著.因此,淫羊藿藥材標準化應該從以下幾箇方麵研究:①對野生資源進行繫統地調查和評估,篩選活性成分相關的優良遺傳資源;②進行種質改良,培育優良新品種,推進中藥材品種標準化;③研究適宜的栽培條件和栽培技術,為GAP基地建設和中藥質量標準化提供物質基礎和技術基礎.
대아국부분시수음양곽약재적주요활성성분진행추양검측증명:불동지구음양곽약재성분함량차이겁현저,음양곽감、조곽정A、B、C사충성분총함량재1.49%~6.96%지간,총황동변이재4.15%~9.66%지간.부분약재사충황동총함량화총황동함량저우약전표준.재불동지구채집적약전규정적오충음양곽약재재성분조성화함량방면차이겁현저,사충황동총함량변이재2.08%~5.38%지간;이무산음양곽위례,불동산지화동일산지적무산음양곽약재개체간재사충황동조성상유명현차이,재사충황동총함량화총황동함량상차이겁현저.인차,음양곽약재표준화응해종이하궤개방면연구:①대야생자원진행계통지조사화평고,사선활성성분상관적우량유전자원;②진행충질개량,배육우량신품충,추진중약재품충표준화;③연구괄의적재배조건화재배기술,위GAP기지건설화중약질량표준화제공물질기출화기술기출.
There are very significant differences on the main active components among Epimedium Drugs from different markets.The total contents of Icariin and Epimedin A , B and C varied from 1.49%to 6. 96%.Some of them are under the standard of China pharmacopoeia .Very significant differences also exist among the Epimedium Drugs of five species stated by China pharmacopoeia .The total contents of Icariin and Epimedin A , B and C varied from 2.08%to 5.38%;within the species of Epimedium wushanense, there exist variations on contents of the main active components and constitute of Icariin and Epimedin A , B and C between different plants from different areas .So the method for standardization of Epimedium Drugs should be:①systematic investigation on the wild Epimedium resources and screening of excellent germ plasms based on the main active components;②breeding research based on the systematic resource investigation for variety standardization;③GAP research for drug standardization .