CAJ | 학술논문

目的：探讨超声实时组织弹性成像诊断慢性乙型肝炎肝纤维化的灵敏度及特异度，分析其临床应用价值。方法：选取在我院就诊并有肝穿刺病理学检查结果的慢性乙型肝炎患者60例。结果：60例患者肝纤维化病理分期S0期19例、S1期16例、S2期10例、S3期7例和S4期8例；超声实时组织弹性成像评分1分20例、2分16例、3分10例、4分7例及5分7例。病理结果显示肝纤维化41例、无肝纤维化19例；超声实时组织弹性成像评分判定肝纤维化40例、无肝纤维化20例。超声实时组织弹性成像灵敏度92．68％，特异度89．47％。结论：超声实时组织弹性成像评估慢性乙型肝炎肝纤维化具有较高的灵敏度与特异度，为肝纤维化的临床诊断提供了一种新的手段，并且具有无创，可反复检查，对观察患者病变进展具有重要的意义。
목적：탐토초성실시조직탄성성상진단만성을형간염간섬유화적령민도급특이도，분석기림상응용개치。방법：선취재아원취진병유간천자병이학검사결과적만성을형간염환자60례。결과：60례환자간섬유화병리분기S0기19례、S1기16례、S2기10례、S3기7례화S4기8례；초성실시조직탄성성상평분1분20례、2분16례、3분10례、4분7례급5분7례。병리결과현시간섬유화41례、무간섬유화19례；초성실시조직탄성성상평분판정간섬유화40례、무간섬유화20례。초성실시조직탄성성상령민도92．68％，특이도89．47％。결론：초성실시조직탄성성상평고만성을형간염간섬유화구유교고적령민도여특이도，위간섬유화적림상진단제공료일충신적수단，병차구유무창，가반복검사，대관찰환자병변진전구유중요적의의。
Objective:To investigate the sensitivity and specificity of ultrasound real-time tissue elas-tography in diagnosing hepatic fibrosis secondary to chronic hepatitis B and analyze the clinical application value .Method:60 patients with chronic hepatitis B examined by liver biopsy pathological examination in our hospital.Result:Among 60 patients, 19 were pathologically staged at So of hepatic fibrosis , 16 at S1 stage, 10 at S2 stage, 7 at S3 stage and 8 at S4;20 were scored 1 by ultrasound real-time tissue elastography , 16 cases scored 2, 10 cases scored 3, 7 cases scored 4 and 7 cases scored 5.As revealed by pathological re-sults, 41 cases had hepatic fibrosis and 19 cases had no hepatic fibrosis;as judged by ultrasound real-time tissue elastography score , 40 cases had hepatic fibrosis and 20 cases had no hepatic fibrosis .The sensitivity of ultrasound real-time tissue elastography was 92.68%and the specificity was 89.47%.Conclusion:Using ultrasound real-time tissue elastography to evaluate hepatic fibrosis secondary to chronic hepatitis B has com-paratively high sensitivity and specificity , which is a new method for clinical diagnosis of hepatic fibrosis , non-invasive and repeatable , and has an important significance for lesion development observation in the pa-tients.