CAJ | 학술논문

目的：比较超短效与短效胰岛素经胰岛素泵皮下输注治疗2型糖尿病的临床疗效。方法：选取我院2009年2月至2012年10月收治的70例2型糖尿病患者按照随机数字表法随机分为A组与B组各35例，分别给予经胰岛素泵皮下输注超短效胰岛素、短效胰岛素治疗，治疗期间均采用动态血糖监测系统进行血糖水平监测，治疗4周后比较两组患者各项指标变化。结果：两组患者FP G、2hPG及睡前血糖水平治疗前、治疗后组间比较无明显差异（P＞0．05），但A组达标时间及胰岛素用量显著少于B组（ P＜0．01）；两组患者治疗前各项指标比较无明显差异（ P＞0．05），治疗后A组较治疗前、同期B组血糖均值、血糖标准差、血糖≤3．9mmoL/L时间百分比均明显低于B组（ P＜0．05），具有统计学意义。结论：超短效胰岛素经胰岛素泵皮下输注治疗2型糖尿病具有疗效佳、安全性高等优点，值得推广应用。
목적：비교초단효여단효이도소경이도소빙피하수주치료2형당뇨병적림상료효。방법：선취아원2009년2월지2012년10월수치적70례2형당뇨병환자안조수궤수자표법수궤분위A조여B조각35례，분별급여경이도소빙피하수주초단효이도소、단효이도소치료，치료기간균채용동태혈당감측계통진행혈당수평감측，치료4주후비교량조환자각항지표변화。결과：량조환자FP G、2hPG급수전혈당수평치료전、치료후조간비교무명현차이（P＞0．05），단A조체표시간급이도소용량현저소우B조（ P＜0．01）；량조환자치료전각항지표비교무명현차이（ P＞0．05），치료후A조교치료전、동기B조혈당균치、혈당표준차、혈당≤3．9mmoL/L시간백분비균명현저우B조（ P＜0．05），구유통계학의의。결론：초단효이도소경이도소빙피하수주치료2형당뇨병구유료효가、안전성고등우점，치득추엄응용。
Objective:To compare the clinical efficacy of ultra short-term effect insulin and short-term effect insulin in the treatment of type 2 diabetes by insulin pump subcutaneous infusion .Method:70 cases of type 2 diabetes patients in our hospital from Feb .2009 to Oct.2012 were selected ,they were randomly divid-ed into group A and group B , with 35 cases in each group , They were treated with ultra short-term effect in-sulin and short-term effect insulin by insulin pump subcutaneous infusion .They were all used continuous glucose monitoring system to monitor blood glucose levels , all indexes were compared between the two groups after 4 weeks treatment .Result:FPG, 2hPG and bedtime blood glucose levels of the two groups had no sig-nificant difference from that before treatment and after treatment (P>0.05), but the standard time and the dosage of insulin in group A were significantly less than that in group B ( P<0.01);All the indexes of the two groups of patients had no significant difference from that before treatment ( P>0.05).After treatment mean blood glucose , blood glucose , blood sugar percentage standard deviation of time was less than 3.9mmoL/L in group A were significantly lower than before treatment and the same period group B (P<0.05), with statisti-cal significance .Conclusion:The ultra short-term effect insulin by subcutaneous infusion of insulin pump has good curative effect , high security in the treatment of type 2 diabetes , it is worthy of popularization and application .