河北医学
河北醫學
하북의학
HEBEI MEDICINE
2014年
3期
488-491
,共4页
周宇%罗良德%杨建%申红
週宇%囉良德%楊建%申紅
주우%라량덕%양건%신홍
食管恶性狭窄%扩张疗法%食管覆膜支架置入%临床疗效
食管噁性狹窄%擴張療法%食管覆膜支架置入%臨床療效
식관악성협착%확장요법%식관복막지가치입%림상료효
Esophageal malignant stricture%Expansion therapy%Esophageal covered stent place-ment%Curative effect
目的：对比食管覆膜支架置入与扩张疗法治疗食管恶性狭窄的疗效和安全性。方法：68例食管恶性狭窄随机分为对照组和观察组，每组各为34例。对照组置入沙氏扩张探条；观察组置入镍钛记忆合金食道覆膜支架。比较两组置入成功率、疗效、梗阻改善状况、术后生活质量及并发症状情况。结果：观察组术后显效率和总有效分别达到82．36％和94．12％，显著高于对照组（ P＜0．05）；观察组术后QOL生活质量评分为（42．30±6．52）分，显著高于术前和对照组术后评分（P＜0．05）；观察组术后总并发症率为8．82％，显著低于对照组并发症率14．71％（P＜0．05），再狭窄率仅为5．88％，显著低于对照的14．71％（ P＜0．05）。结论：内镜下食管覆膜支架置入治疗食管恶性狭窄成功率高，能迅速缓解吞咽困难，术后患者生存质量高，并发症少，综合疗效显著优于沙氏扩张探条扩张。
目的：對比食管覆膜支架置入與擴張療法治療食管噁性狹窄的療效和安全性。方法：68例食管噁性狹窄隨機分為對照組和觀察組，每組各為34例。對照組置入沙氏擴張探條；觀察組置入鎳鈦記憶閤金食道覆膜支架。比較兩組置入成功率、療效、梗阻改善狀況、術後生活質量及併髮癥狀情況。結果：觀察組術後顯效率和總有效分彆達到82．36％和94．12％，顯著高于對照組（ P＜0．05）；觀察組術後QOL生活質量評分為（42．30±6．52）分，顯著高于術前和對照組術後評分（P＜0．05）；觀察組術後總併髮癥率為8．82％，顯著低于對照組併髮癥率14．71％（P＜0．05），再狹窄率僅為5．88％，顯著低于對照的14．71％（ P＜0．05）。結論：內鏡下食管覆膜支架置入治療食管噁性狹窄成功率高，能迅速緩解吞嚥睏難，術後患者生存質量高，併髮癥少，綜閤療效顯著優于沙氏擴張探條擴張。
목적：대비식관복막지가치입여확장요법치료식관악성협착적료효화안전성。방법：68례식관악성협착수궤분위대조조화관찰조，매조각위34례。대조조치입사씨확장탐조；관찰조치입얼태기억합금식도복막지가。비교량조치입성공솔、료효、경조개선상황、술후생활질량급병발증상정황。결과：관찰조술후현효솔화총유효분별체도82．36％화94．12％，현저고우대조조（ P＜0．05）；관찰조술후QOL생활질량평분위（42．30±6．52）분，현저고우술전화대조조술후평분（P＜0．05）；관찰조술후총병발증솔위8．82％，현저저우대조조병발증솔14．71％（P＜0．05），재협착솔부위5．88％，현저저우대조적14．71％（ P＜0．05）。결론：내경하식관복막지가치입치료식관악성협착성공솔고，능신속완해탄인곤난，술후환자생존질량고，병발증소，종합료효현저우우사씨확장탐조확장。
Objective:To compare the efficacy and safety between the Esophageal covered stent place-ment and expansion therapy on the cases with esophageal malignant stricture .Method:68 patients with ma-lignant esophageal stenosis were randomly divided into the control group and the observation group , each group had 34 cases.The control groups were implanted with Salmonella dilating bougie while the observation groups were implanted with nickel titanium memory alloy esophageal stent .The placement success rate , effi-cacy, the improvement of obstruction , the quality of life and complication after operation between two groups were compared .Results:The effective rate and total effective in the observation group reached 82.36%and 94.12%respectively, significantly higher than that of the control group (P<0.05).The QOL quality of life score in the observation groups after treatment was (42.30 ±6.52) points, significantly higher than that of the preoperative and postoperative scores of the control groups (P<0.05).The total the complication rate of the observation group was 8.82%, significantly lower than that of the control group ( P<0.05) and restenosis rate was only 5.88%, significantly lower than that of the control (P<0.05).Conclusion: The Esophageal covered stent placement implanted on the esophageal malignant stricture had high success rate , with high quality of life and fewer complications , the curative effect was significantly better than the Sand's expansion bougienage .
