CAJ | 학술논문

目的：了解本地区近2年来不孕不育患者生殖道支原体感染及耐药情况。方法对我院2011~2013年在生殖门诊就诊并进行支原体培养、鉴定及药敏试验的患者进行统计分析。结果848份标本中支原体阳性的410例，其中解脲支原体（Uu）阳性370例。女性患者Uu感染率45.6%（351/769），男性患者感染率24.1%(19/79)。药敏结果显示环丙沙星和氧氟沙星的耐药率分别为89.0%和73.3%，而强力霉素、原始霉素、四环素及交沙霉素的敏感性均达90%以上。结论本地区不孕不育患者支原体感染率较高，男性与女性感染率有显著差异。支原体对环丙沙星及氧氟沙星耐药率较高，提示临床治疗时必须进行相应的药物敏感性试验，合理选用抗生素，以达到有效治疗的目的。
목적：료해본지구근2년래불잉불육환자생식도지원체감염급내약정황。방법대아원2011~2013년재생식문진취진병진행지원체배양、감정급약민시험적환자진행통계분석。결과848빈표본중지원체양성적410례，기중해뇨지원체（Uu）양성370례。녀성환자Uu감염솔45.6%（351/769），남성환자감염솔24.1%(19/79)。약민결과현시배병사성화양불사성적내약솔분별위89.0%화73.3%，이강력매소、원시매소、사배소급교사매소적민감성균체90%이상。결론본지구불잉불육환자지원체감염솔교고，남성여녀성감염솔유현저차이。지원체대배병사성급양불사성내약솔교고，제시림상치료시필수진행상응적약물민감성시험，합리선용항생소，이체도유효치료적목적。
Objective to investigate the infection of genital tract derived Mycoplasma and antibiotic resistance in local area infertility patients. Methods By statistical analysis,the patients who had visited in sterility clinic from 2011~2013 and tested for genital tract Mycoplasma were analyzed. Results In the total 848 tested samples, there was 410 positive results,and 370 patients were infection by Ureaplasma urealytium.Uu infection rates in male and female were 45.6% and 24.1% respectively.Drug susceptibility analysis showed the resistance rate of Ciprofloxacin and Ofloxacin were 89.0% and 73.3% respectively.The drugs with high susceptibility were Doxycycline, Pristinamycin,Tetracycline and Josamycin,the susceptibility rate of these drugs reached to above 90%. Conclusion The genital tract Uu infection rate of infertility patients and the resistance rate of Ciprofloxacin and Ofloxacin is higher in local area.The infection rates in male and female were significant dif erence.So the clinic treat should be according to the drug sensitivity test results.