CAJ | 학술논문

目的：探讨肠球菌所致急性肾盂肾炎的耐药性基因，探讨治疗对策，指导临床合理用药。方法选取我院2012年5月~2013年6月收治的有肠球菌导致的急性肾盂肾炎患者常规培养检出148株肠球菌为研究对象，分析其耐药性。结果148株肠球菌属构成比例为：粪肠球菌72株（48.65%）；尿肠球菌55株（37.16%）；鸟肠球菌17株（11.49%）；其他肠球菌4株（2.70%）。粪肠球菌对利福平、四环素、红霉素耐药率＞70%。尿肠球菌对左氧氟沙星、青霉素、安卡西林、红霉素、呋喃妥因耐药率达到70%以上。尿肠球菌对红霉素、氨苄西林耐药率达到70%以上。结论随着社会的发展和一些用药的不同，肠球菌的耐药性也在不断的增强，而且肠球菌也有很多种不同的类型，就它的这种中间差异性来说，一些抗生素的耐药性也不同，这也是如今比较严重的问题，在此同时也预示着临床上药根据肠球菌的耐药不同，来有针对性的去选择抗生素。药物的使用在不断的增多，药物的药效也在逐渐的增强，由此导致肠球菌不断地演变，分化的菌种类型增多，其耐药性也不断的增强，因此在治疗肠球菌所引发的疾病时，应根据不同肠球菌的耐药性，选择合适的治疗方法，减少临床上的治疗错误。
목적：탐토장구균소치급성신우신염적내약성기인，탐토치료대책，지도림상합리용약。방법선취아원2012년5월~2013년6월수치적유장구균도치적급성신우신염환자상규배양검출148주장구균위연구대상，분석기내약성。결과148주장구균속구성비례위：분장구균72주（48.65%）；뇨장구균55주（37.16%）；조장구균17주（11.49%）；기타장구균4주（2.70%）。분장구균대리복평、사배소、홍매소내약솔＞70%。뇨장구균대좌양불사성、청매소、안잡서림、홍매소、부남타인내약솔체도70%이상。뇨장구균대홍매소、안변서림내약솔체도70%이상。결론수착사회적발전화일사용약적불동，장구균적내약성야재불단적증강，이차장구균야유흔다충불동적류형，취타적저충중간차이성래설，일사항생소적내약성야불동，저야시여금비교엄중적문제，재차동시야예시착림상상약근거장구균적내약불동，래유침대성적거선택항생소。약물적사용재불단적증다，약물적약효야재축점적증강，유차도치장구균불단지연변，분화적균충류형증다，기내약성야불단적증강，인차재치료장구균소인발적질병시，응근거불동장구균적내약성，선택합괄적치료방법，감소림상상적치료착오。
Objective:Investigate the drug resistance of enterococcus caused by acute pyelonephritis genes,treatment countermeasures is discussed,and to guide clinical rational drug use. Methods:Select our hospital from May 2012 to June 2012 treated with enterococcus in patients with acute pyelonephritis regular train detection 148 strains enterococcus as the research object,Analysis of the resistance. Results:148 strains of enterococcus belong to constitute ratio for:Dung enterococcus72strains (48.65%);Urine 55 strains enterococcus (37.16%); Bird 17 strains enterococcus (11.49%);The other 4 strains enterococcus (2.70%). Dung enterococcus of rifampicin, Tetracycline, Erythromycin resistant rate > 70%. Urine enterococcus of levofloxacin,Westwood, erythromycin,penicil in,anka,with nitrofurantoin due to resistance to reach more than 70%. Conclusion:With the development of the society and some of the medication is dif erent,The drug resistance of enterococcus have been enhanced, And also there are many dif erent types of enterococcus,Is it in the middle of this dif erence,Some antibiotics resistance is dif erent also,This is serious problem nowadays,At the same time also foreshadowed the clinical prescription according to the drug resistance of enterococcus is dif erent,To targeted to choose antibiotics.Drug use is constantly increasing,the ef ects of the drug are also gradual y enhanced,leading to bowel coccus continuously evolution,increase in the number of strains of type dif erentiation,its resistance also constantly strengthen,therefore in the treatment of the diseases caused by enterococcus,should according to dif erent drug resistance of enterococcus,select the appropriate treatment,reduce the clinical medication errors.