中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
27期
4-6
,共3页
黄权芳%林兴%韦振源%刘倩%言开武
黃權芳%林興%韋振源%劉倩%言開武
황권방%림흥%위진원%류천%언개무
正交试验%提取工艺%感冒药茶颗粒
正交試驗%提取工藝%感冒藥茶顆粒
정교시험%제취공예%감모약다과립
Orthogonal test%Extraction process%Ganmao Yaocha Granules
目的:优选感冒药茶颗粒的提取工艺,以便制备质量稳定的制剂。方法以加水量,提取时间,提取次数为考察因素,以总黄酮及熊果酸和浸膏量为指标,采用L9(3)4正交试验法对感冒药茶颗粒的最佳提取工艺进行优选。结果该制剂最佳提取工艺为加水量10倍,提取3次,每次提取时间60min。结论该提取工艺合理可行,稳定可控,适用于大生产,是最佳制备工艺。
目的:優選感冒藥茶顆粒的提取工藝,以便製備質量穩定的製劑。方法以加水量,提取時間,提取次數為攷察因素,以總黃酮及熊果痠和浸膏量為指標,採用L9(3)4正交試驗法對感冒藥茶顆粒的最佳提取工藝進行優選。結果該製劑最佳提取工藝為加水量10倍,提取3次,每次提取時間60min。結論該提取工藝閤理可行,穩定可控,適用于大生產,是最佳製備工藝。
목적:우선감모약다과립적제취공예,이편제비질량은정적제제。방법이가수량,제취시간,제취차수위고찰인소,이총황동급웅과산화침고량위지표,채용L9(3)4정교시험법대감모약다과립적최가제취공예진행우선。결과해제제최가제취공예위가수량10배,제취3차,매차제취시간60min。결론해제취공예합리가행,은정가공,괄용우대생산,시최가제비공예。
Objective To optimize techniques for Ganmao Yaocha granule, Preparation and stability so as to the quality of preparation. Methods The amount of water, extraction time and frequency as variables, By taking the rate of extract and the total of lfavonoids, ursolic as the indexes components, the extraction techniques were optimized for Compound rhubarb enema through L9(3)4orthogonal test. Results The best condition is 3 times to boil with water, each 10 times,1 hours. Conclusion The preparation technology is feasible and reliable for the manufacturing process of Compound rhubarb enema.