CAJ | 학술논문

目的：探讨恩度静脉滴注联合介入化疗栓塞治疗中晚期肝癌的临床疗效。方法本文将39例原发性肝癌患者随机分为观察组和对照组，其中观察组采用恩度静脉滴注联合介入化疗栓塞治疗，并与单独采用介入化疗栓塞治疗的对照组进行临床疗效比较。结果恩度联合TACE治疗肝癌的总有效率较对照组高，恩度联合TACE治疗组患者无病进展生存期高于对照组，差异有统计学意义（P＜0.05）。另外，两组的不良反应相似。结论恩度联合TACE是治疗中晚期肝癌一种有效的、安全的方法，值得进一步开展随机对照研究。
목적：탐토은도정맥적주연합개입화료전새치료중만기간암적림상료효。방법본문장39례원발성간암환자수궤분위관찰조화대조조，기중관찰조채용은도정맥적주연합개입화료전새치료，병여단독채용개입화료전새치료적대조조진행림상료효비교。결과은도연합TACE치료간암적총유효솔교대조조고，은도연합TACE치료조환자무병진전생존기고우대조조，차이유통계학의의（P＜0.05）。령외，량조적불량반응상사。결론은도연합TACE시치료중만기간암일충유효적、안전적방법，치득진일보개전수궤대조연구。
Objective?To investigate the involvement Endostar infusion chemotherapy and embolization in treatment of advanced liver cancer patients. Methods 39 patients with primary liver cancer were randomly divided into two groups and the control group. The observation group was intervened by Endostar infusion chemotherapy and embolization interventional therapy, and compared with the control group which was intervened with the single chemotherapy and embolization interventional therapy. Results The total efficacy rate of endostar combined TACE in treatment of advanced liver cancer were significantly higher than the single use of TACE in control group, there was significant difference (P<0.05). PFS of endostar combined TACE in treatment of advanced liver cancer were significantly higher than the single use of TACE in control group, there was significant difference (P<0.05). In addition, the adverse effects were similar in both groups.Conclusion The combined intervention Endostar infusion chemotherapy and embolization in treatment of advanced liver cancer is an effective method of treatment, and it could be popularized in clinical.