CAJ | 학술논문

颅脑损伤是一种常见的、死残率较高的损伤，而颅脑损伤后凝血-纤溶功能异常的发生率40％~80％，在中、重型颅脑损伤中，凝血异常发生率为27%～93%[1]。如何降低颅脑损伤患者的死、残率，提高患者生存质量，是目前神经外科的研究重点之一。而凝血-纤溶指标紊乱是颅脑损伤常见并发症，可加重脑损害并影响患者预后，对这些指标进行监测，有利于临床治疗策略的制定及对预后的评估。本文就颅脑损伤后凝血-纤溶指标变化机制，其对患者预后评估价值及目前针对颅脑损伤后凝血功能不全的治疗作一综述。
로뇌손상시일충상견적、사잔솔교고적손상，이로뇌손상후응혈-섬용공능이상적발생솔40％~80％，재중、중형로뇌손상중，응혈이상발생솔위27%～93%[1]。여하강저로뇌손상환자적사、잔솔，제고환자생존질량，시목전신경외과적연구중점지일。이응혈-섬용지표문란시로뇌손상상견병발증，가가중뇌손해병영향환자예후，대저사지표진행감측，유리우림상치료책략적제정급대예후적평고。본문취로뇌손상후응혈-섬용지표변화궤제，기대환자예후평고개치급목전침대로뇌손상후응혈공능불전적치료작일종술。
Craniocerebral injury is a common injury, the death rate is higher, and dysfunction of blood coagulation, fibrinolytic after craniocerebral injury incidence of 40%80%, in the medium and heavy craniocerebral injury, coagulation abnormality rate was 27%~93% [1].How to reduce the rate of death in patients with craniocerebral injury and residual rate, improve the quality of survival, is one of the research focus of neurosurgery at present. And coagulation, fibrinolytic indexes disorder is a common complication, craniocerebral injury can worsen the prognosis of patients with brain damage and impact, to monitor these metrics, is helpful to clinical treatment strategy formulation and evaluation of prognosis. In this paper, the coagulation, fibrinolytic indexes change after craniocerebral injury mechanisms, and prognosis of patients with the assessed value of the current and blood coagulation dysfunction treatment after craniocerebral injury.