中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
3期
324-326
,共3页
郭璐%周善璧%赵敏%张琪
郭璐%週善璧%趙敏%張琪
곽로%주선벽%조민%장기
眼表烧伤%结膜囊%细菌培养
眼錶燒傷%結膜囊%細菌培養
안표소상%결막낭%세균배양
Ocular surface burns%Conjunctival sac%Germiculture,Drug sensitivity test
目的 了解烧伤状态下结膜囊的带菌情况,为其预防性使用抗感染药品提供依据.方法 对2011年6月至2013年3月在重庆医大第一医院眼科就治的眼表烧伤患者(26只烧伤眼)及自愿者(25只正常眼)的结膜囊进行细菌培养和药物敏感试验,并对其结果进行分析.结果 眼表烧伤患者患眼结膜囊细菌阳性率为53.85％ (14/26),对照组正常结膜囊细菌阳性率为56.00％ (14/25),2组比较差异无统计学意义(x2=0.024,P=0.877).烧伤眼(26只眼)与正常眼(25只眼)均培养出2个菌种,5个菌株.正常眼所检出的14例阳性菌株中,革兰阳球菌占92.86％(13/14),其次为革兰阳性杆菌,占7.14％ (1/14).阳性菌株中表皮葡萄球菌为64.29％ (9/14),头状葡萄球菌14.29％ (2/14).烧伤眼结膜囊检出的14例阳性菌株,主要由革兰阳球菌构成为92.86％ (13/14),其次为革兰阳性杆菌占7.14％ (1/14).阳性菌株中表皮葡萄球菌42.86％ (6/14),溶血葡萄球菌35.74％ (5/14).2组结膜囊优势菌种均以表皮葡萄球菌为主.烧伤眼表皮葡萄球菌占总检出阳性菌株的42.86％(6/14),较正常组的64.29％ (9/14)低,差异无统计学意义(P =0.449,P＞0.05);烧伤眼溶血性葡萄球菌阳性检出率明显高于正常跟,2组差异有统计学意义(P =0.041,P＜0.05).结论 烧伤眼与正常眼结膜囊内的细菌为常居菌.2组细菌阳性检出率、菌种数、革兰分类的构成比相似.但较于正常眼,烧伤眼结膜囊溶血葡萄球菌阳性率明显增高.其高检出率提示烧伤眼结膜囊的微环境可能已发生改变.故烧伤患者治疗过程中,应常规进行结膜囊细菌培养,并根据其结果选择敏感抗生素防止感染.
目的 瞭解燒傷狀態下結膜囊的帶菌情況,為其預防性使用抗感染藥品提供依據.方法 對2011年6月至2013年3月在重慶醫大第一醫院眼科就治的眼錶燒傷患者(26隻燒傷眼)及自願者(25隻正常眼)的結膜囊進行細菌培養和藥物敏感試驗,併對其結果進行分析.結果 眼錶燒傷患者患眼結膜囊細菌暘性率為53.85％ (14/26),對照組正常結膜囊細菌暘性率為56.00％ (14/25),2組比較差異無統計學意義(x2=0.024,P=0.877).燒傷眼(26隻眼)與正常眼(25隻眼)均培養齣2箇菌種,5箇菌株.正常眼所檢齣的14例暘性菌株中,革蘭暘毬菌佔92.86％(13/14),其次為革蘭暘性桿菌,佔7.14％ (1/14).暘性菌株中錶皮葡萄毬菌為64.29％ (9/14),頭狀葡萄毬菌14.29％ (2/14).燒傷眼結膜囊檢齣的14例暘性菌株,主要由革蘭暘毬菌構成為92.86％ (13/14),其次為革蘭暘性桿菌佔7.14％ (1/14).暘性菌株中錶皮葡萄毬菌42.86％ (6/14),溶血葡萄毬菌35.74％ (5/14).2組結膜囊優勢菌種均以錶皮葡萄毬菌為主.燒傷眼錶皮葡萄毬菌佔總檢齣暘性菌株的42.86％(6/14),較正常組的64.29％ (9/14)低,差異無統計學意義(P =0.449,P＞0.05);燒傷眼溶血性葡萄毬菌暘性檢齣率明顯高于正常跟,2組差異有統計學意義(P =0.041,P＜0.05).結論 燒傷眼與正常眼結膜囊內的細菌為常居菌.2組細菌暘性檢齣率、菌種數、革蘭分類的構成比相似.但較于正常眼,燒傷眼結膜囊溶血葡萄毬菌暘性率明顯增高.其高檢齣率提示燒傷眼結膜囊的微環境可能已髮生改變.故燒傷患者治療過程中,應常規進行結膜囊細菌培養,併根據其結果選擇敏感抗生素防止感染.
목적 료해소상상태하결막낭적대균정황,위기예방성사용항감염약품제공의거.방법 대2011년6월지2013년3월재중경의대제일의원안과취치적안표소상환자(26지소상안)급자원자(25지정상안)적결막낭진행세균배양화약물민감시험,병대기결과진행분석.결과 안표소상환자환안결막낭세균양성솔위53.85％ (14/26),대조조정상결막낭세균양성솔위56.00％ (14/25),2조비교차이무통계학의의(x2=0.024,P=0.877).소상안(26지안)여정상안(25지안)균배양출2개균충,5개균주.정상안소검출적14례양성균주중,혁란양구균점92.86％(13/14),기차위혁란양성간균,점7.14％ (1/14).양성균주중표피포도구균위64.29％ (9/14),두상포도구균14.29％ (2/14).소상안결막낭검출적14례양성균주,주요유혁란양구균구성위92.86％ (13/14),기차위혁란양성간균점7.14％ (1/14).양성균주중표피포도구균42.86％ (6/14),용혈포도구균35.74％ (5/14).2조결막낭우세균충균이표피포도구균위주.소상안표피포도구균점총검출양성균주적42.86％(6/14),교정상조적64.29％ (9/14)저,차이무통계학의의(P =0.449,P＞0.05);소상안용혈성포도구균양성검출솔명현고우정상근,2조차이유통계학의의(P =0.041,P＜0.05).결론 소상안여정상안결막낭내적세균위상거균.2조세균양성검출솔、균충수、혁란분류적구성비상사.단교우정상안,소상안결막낭용혈포도구균양성솔명현증고.기고검출솔제시소상안결막낭적미배경가능이발생개변.고소상환자치료과정중,응상규진행결막낭세균배양,병근거기결과선택민감항생소방지감염.
Objective To understand the bacteria status in the conjunctival sac with ocular surface burns,for the treatment of infection and aseptic preparation before operation.Methods A total of 26 eyes with ocular surface bums in our hospital were examined,and another 25 normal eyes in the same crowd were analyzed as the control group.Then,the results of bacterial culture results and drug sensitivity test were analyzed.Results The positive rate of the cultivation was 53.85％ (14/26) in ocular surface bums eyes,and 56％ (14/25) in normal eyes.There was no statistical difference between two groups (x2=0.024,P =0.877).In two groups of conjunctival sac,5 species bacteria were cultivated,Gram-positive bacteria in 13 eyes (92.86％),Gram-negative bacteria in 1 eye (7.14％).There were 9 Staphylococcus epidermidis strains (64.29％) and Staphylococcus capitis 2 strains (14.29％) in bum eyes group.In control group,there were 6 Staphylococcus epidermidis strains (42.86％),5 strains of Staphylococcus haernolyticus (35.74％).Two groups of conjunctival sac advantage strains were mainly Staphylococcus epidermidis.The positive rate of bum eyes of Staphylococcus epidermidis was 42.86％.It was lower than the normal group (64.29％).There was no statistical difference of positive rate between two groups (P =0.449).The positive rate of bum eyes of Staphylococcus haemolyticus was significantly higher than that in normal eyes.There was statistical difference of positive rate between two groups (P =0.041).Conjunctival bacteria (coagnlase negative Staphylococcus) in bum eyes group resisted to the commonly used in clinical drug,such as penicillin,ciprofloxacin,erythromycin; sensitive to moxifioxacin,gentamicin.Conclusions There is no influence whether or not with ocular surface bums in bacterial positive rate,the number of bacterial species,the constituent ratio of Gram classification and dominant strain.Compared with the normal eyes,the positive rate of burn of conjunctival sac hemolytic Staphylococcus is increased.The bacterial culture of conjunctiva sac is necessary for treatment of ocular surface burns patients.And sensitive antibiotics shall be used to prevent eye infections.
