CAJ | 학술논문

目的：探讨静脉滴注地尔硫卓治疗不稳定型心绞痛的临床效果及安全性，进一步指导临床治疗。方法：选取2010年1月-2012年1月本院收治的不稳定型心绞痛患者90例进行研究，随机分为观察组和对照组各45例。对照组患者采用常规治疗，包括硝酸盐、阿司匹林、β受体阻滞剂和钙离子拮抗剂等；观察组在常规治疗的基础上，采用地尔硫卓进行静脉滴注治疗；对两组患者的治疗效果和不良反应发生情况进行对比分析。结果：观察组治疗有效率93.3%（42/45）高于对照组的73.3%（33/42），差异具有统计学意义（P<0.05）；两组不良反应发生率比较差异具有统计学意义（P<0.05）。结论：在常规治疗的基础上，加用地尔硫卓进行静脉滴注治疗，能够有效提高不稳定型心绞痛的临床效果，其不良反应少，安全性较高，值得在临床进行推广应用。
목적：탐토정맥적주지이류탁치료불은정형심교통적림상효과급안전성，진일보지도림상치료。방법：선취2010년1월-2012년1월본원수치적불은정형심교통환자90례진행연구，수궤분위관찰조화대조조각45례。대조조환자채용상규치료，포괄초산염、아사필림、β수체조체제화개리자길항제등；관찰조재상규치료적기출상，채용지이류탁진행정맥적주치료；대량조환자적치료효과화불량반응발생정황진행대비분석。결과：관찰조치료유효솔93.3%（42/45）고우대조조적73.3%（33/42），차이구유통계학의의（P<0.05）；량조불량반응발생솔비교차이구유통계학의의（P<0.05）。결론：재상규치료적기출상，가용지이류탁진행정맥적주치료，능구유효제고불은정형심교통적림상효과，기불량반응소，안전성교고，치득재림상진행추엄응용。
Objective:To explore the intravenous diltiazem treatment of unstable angina clinical efficacy and safety,and further guide clinical treatment. Method:From January 2010 to January 2012 between the treated 90 patients with unstable angina were studied and randomly divided into observation group and control group,45 cases in control group were treated by routine therapy,included nitrate,aspirin,beta blockers and calcium antagonists;observation group on the basis of routine therapy,with diltiazem intravenous drip treatment,the treatment effect and adverse reactions occur of two groups were observed and compared. Result:The observation group effectiveness was 93.3%(42/45),control group was effectiveness 73.3%(33/45),the difference compared had statistically significant difference(P<0.05);incidence of adverse reactions compared between the two groups had statistically significant(P<0.05). Conclusion:On the basis of conventional treatment,and use diltiazem for intravenous drip treatment,can effectively improve the clinical effect of unstable angina,less adverse reaction and safety is higher,is worth popularizing in clinical application.