中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
31期
120-121
,共2页
阿托伐他汀%血脂%冠心病
阿託伐他汀%血脂%冠心病
아탁벌타정%혈지%관심병
Atorvastatin%Lipid%Coronary artery disease
目的:分析阿托伐他汀对老年血脂正常冠心病患者治疗疗效及预后影响。方法:选择本院在2005年2月-2012年6月收治的540例老年血脂正常冠心病患者,按入院顺序分为观察组270例和对照组270例,其中对照组采用常规治疗,对照组采用在常规治疗基础上加用阿托伐他汀治疗,然后观察两组患者的疗效及预后。结果:观察组治疗总有效率94.07%明显高于对照组的81.85%,观察组的临床疗效明显优于对照组患者,比较差异有统计学意义(P<0.05)。观察组6个月内心绞痛发生率6.67%明显低于对照组的19.62%,急性心肌梗死发生率2.59%明显低于对照组的6.30%,严重心律失常发生率1.11%明显低于对照组的7.78%,心源性死亡发生率0.74%明显低于对照组的1.85%,心血管事件总发生率11.11%明显低于对照组的35.56%。由此可得观察组患者的心血管事件发生情况明显低于对照组,比较差异均有统计学意义(P<0.05)。结论:阿托伐他汀能提高老年血脂正常冠心病患者治疗疗效、改善患者的预后、值得临床推广应用。
目的:分析阿託伐他汀對老年血脂正常冠心病患者治療療效及預後影響。方法:選擇本院在2005年2月-2012年6月收治的540例老年血脂正常冠心病患者,按入院順序分為觀察組270例和對照組270例,其中對照組採用常規治療,對照組採用在常規治療基礎上加用阿託伐他汀治療,然後觀察兩組患者的療效及預後。結果:觀察組治療總有效率94.07%明顯高于對照組的81.85%,觀察組的臨床療效明顯優于對照組患者,比較差異有統計學意義(P<0.05)。觀察組6箇月內心絞痛髮生率6.67%明顯低于對照組的19.62%,急性心肌梗死髮生率2.59%明顯低于對照組的6.30%,嚴重心律失常髮生率1.11%明顯低于對照組的7.78%,心源性死亡髮生率0.74%明顯低于對照組的1.85%,心血管事件總髮生率11.11%明顯低于對照組的35.56%。由此可得觀察組患者的心血管事件髮生情況明顯低于對照組,比較差異均有統計學意義(P<0.05)。結論:阿託伐他汀能提高老年血脂正常冠心病患者治療療效、改善患者的預後、值得臨床推廣應用。
목적:분석아탁벌타정대노년혈지정상관심병환자치료료효급예후영향。방법:선택본원재2005년2월-2012년6월수치적540례노년혈지정상관심병환자,안입원순서분위관찰조270례화대조조270례,기중대조조채용상규치료,대조조채용재상규치료기출상가용아탁벌타정치료,연후관찰량조환자적료효급예후。결과:관찰조치료총유효솔94.07%명현고우대조조적81.85%,관찰조적림상료효명현우우대조조환자,비교차이유통계학의의(P<0.05)。관찰조6개월내심교통발생솔6.67%명현저우대조조적19.62%,급성심기경사발생솔2.59%명현저우대조조적6.30%,엄중심률실상발생솔1.11%명현저우대조조적7.78%,심원성사망발생솔0.74%명현저우대조조적1.85%,심혈관사건총발생솔11.11%명현저우대조조적35.56%。유차가득관찰조환자적심혈관사건발생정황명현저우대조조,비교차이균유통계학의의(P<0.05)。결론:아탁벌타정능제고노년혈지정상관심병환자치료료효、개선환자적예후、치득림상추엄응용。
Objective:To analyze the effect of atorvastatin on curative effect and prognosis in elderly coronary artery disease patients with normal lipid.Method:Five hundred and forty elderly coronary artery disease patients with normal blood lipids in our hospital from February 2005 to June 2012 were selected,according to admission order divided into the observation group and the control group,270 cases in each group,the control group was treated with conventional treatment,the observation group was treated on the basis of conventional treatment combined with atorvastatin therapy,then the curative effect and prognosis of two groups were observed.Result:The total effective rate of observation group was 94.07%,it was significantly higher than the control group(81.85%),clinical curative effect of the observation group was obviously better than the control group,the difference was statistically significant(P<0.05).Angina incidence of the observation group in six months was 6.67%,it was significantly lower than the control group(19.62%), acute myocardial infarction incidence of the observation group was 2.59%,it was significantly lower than the control group(6.30%),severe arrhythmia incidence of the observation group was 1.11%,it was significantly lower than the control group(7.78%),the incidence of cardiac death was 0.74%, it was significantly lower than the control group(1.85%),The total incidence of cardiovascular events was 11.11%,it was significantly lower than the control group(35.56%).The cardiovascular events of the observation group was significantly lower than the control group,there were statistically significant differences between the groups(P<0.05).Conclusion:The atorvastatin can improve the curative effect and prognosis of the elderly coronary artery disease patients.It is worthy to be popularized.