中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
31期
85-86,87
,共3页
氨氯地平%二甲双胍%肥胖%高血压
氨氯地平%二甲雙胍%肥胖%高血壓
안록지평%이갑쌍고%비반%고혈압
Amlodipine%Metformin%Obesity%Hypertension
目的：探讨氨氯地平联合二甲双胍用于肥胖型轻中度高血压治疗的临床效果。方法：选取肥胖型轻中度高血压患者150例，按照随即编号法分为对照组73例和观察组77例。对照组给予氨氯地平治疗，观察组在对照组基础上加用二甲双胍进行治疗。对两组患者的血压控制情况以及多项生活指标进行监测，并评价治疗效果。结果：经过治疗两组患者血压与治疗前相比均明显下降，但观察组患者降低更为明显，而且观察组患者治疗有效率明显高于对照组，比较差异均有统计学意义（P<0.05）。经过治疗，对照组患者仅有HbA1C与治疗前相比明显降低，其他指标与治疗前比较差异无统计学意义（P>0.05）。观察组患者各项指标与治疗前相比均明显降低，且低于对照组患者治疗后，比较差异均有统计学意义（P<0.05）。结论：对伴有肥胖的轻中度高血压患者实施氨氯地平和二甲双胍联合治疗在控制患者血压和血脂方面具有较好的效果，可以作为临床首选的联合用药方案进行推广。
目的：探討氨氯地平聯閤二甲雙胍用于肥胖型輕中度高血壓治療的臨床效果。方法：選取肥胖型輕中度高血壓患者150例，按照隨即編號法分為對照組73例和觀察組77例。對照組給予氨氯地平治療，觀察組在對照組基礎上加用二甲雙胍進行治療。對兩組患者的血壓控製情況以及多項生活指標進行鑑測，併評價治療效果。結果：經過治療兩組患者血壓與治療前相比均明顯下降，但觀察組患者降低更為明顯，而且觀察組患者治療有效率明顯高于對照組，比較差異均有統計學意義（P<0.05）。經過治療，對照組患者僅有HbA1C與治療前相比明顯降低，其他指標與治療前比較差異無統計學意義（P>0.05）。觀察組患者各項指標與治療前相比均明顯降低，且低于對照組患者治療後，比較差異均有統計學意義（P<0.05）。結論：對伴有肥胖的輕中度高血壓患者實施氨氯地平和二甲雙胍聯閤治療在控製患者血壓和血脂方麵具有較好的效果，可以作為臨床首選的聯閤用藥方案進行推廣。
목적：탐토안록지평연합이갑쌍고용우비반형경중도고혈압치료적림상효과。방법：선취비반형경중도고혈압환자150례，안조수즉편호법분위대조조73례화관찰조77례。대조조급여안록지평치료，관찰조재대조조기출상가용이갑쌍고진행치료。대량조환자적혈압공제정황이급다항생활지표진행감측，병평개치료효과。결과：경과치료량조환자혈압여치료전상비균명현하강，단관찰조환자강저경위명현，이차관찰조환자치료유효솔명현고우대조조，비교차이균유통계학의의（P<0.05）。경과치료，대조조환자부유HbA1C여치료전상비명현강저，기타지표여치료전비교차이무통계학의의（P>0.05）。관찰조환자각항지표여치료전상비균명현강저，차저우대조조환자치료후，비교차이균유통계학의의（P<0.05）。결론：대반유비반적경중도고혈압환자실시안록지평화이갑쌍고연합치료재공제환자혈압화혈지방면구유교호적효과，가이작위림상수선적연합용약방안진행추엄。
Objective:To investigate the clinical effect for amlodipine combined with metformin in the treatment of obese mild to moderate hypertension.Method:One hundred and fifty obese patients with mild to moderate hypertension were selected,and they were randomly divided into 73 cases of the control group and 77 cases of the observation group.The control group was treated with amlodipine treatment,and the control group was treated with metformin treatment on the basis of the control group.The blood pressure control and numerous life indicators for monitoring the therapeutic effect of the two groups were evaluated.Result:After treatment,the blood pressure of the two groups decreased significantly compared with before treatment, and the control group was more obvious.The treatment efficacy rate of the observation group was significantly higher than the control group,there were statistically significant differences(P<0.05).After treatment,the HbA1C in the control group was only significantly lower than before treatment.Other indictors compared with before treatment,there were no significant differences(P>0.05).The indicators compared with before treatment in the control group were significantly lower,and lower than the control group after treatment,the differences were obvious,and there were statistically significant differences(P<0.05).Conclusion:The amlodipine metformin in the treatment of obese mild to moderate hypertension has a good effect,can be used as the preferred combination for clinical programs.
