当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
30期
40-41
,共2页
消化性溃疡%幽门螺杆菌%序贯疗法%三联疗法
消化性潰瘍%幽門螺桿菌%序貫療法%三聯療法
소화성궤양%유문라간균%서관요법%삼련요법
Digestive ulcer%Helicobacter pylori%Sequential therapy%Triple therapy
目的：比较序贯疗法和三联疗法治疗幽门螺杆菌阳性溃疡的临床疗效。方法选择2012年3月-2013年1月诊治的幽门螺杆菌阳性溃疡患者72例作为研究对象，按照随机数字表法分为对照组和观察组，各36例。对照组采用三联疗法，观察组采用序贯疗法，比较两组的临床治疗效果。结果观察组患者的溃疡愈合率及幽门螺杆菌根除率分别为91.7%、97.2%，明显高于对照组的72.2%、77.8%，两组间差异有统计学意义（P＜0.05）；两组不良反应发生率分别为5.6%、11.1%，组间差异无统计学意义（P＞0.05）。结论序贯疗法治疗幽门螺杆菌阳性溃疡的临床疗效更佳，具有较高的溃疡愈合率及幽门螺杆菌根除率，且安全性好。
目的：比較序貫療法和三聯療法治療幽門螺桿菌暘性潰瘍的臨床療效。方法選擇2012年3月-2013年1月診治的幽門螺桿菌暘性潰瘍患者72例作為研究對象，按照隨機數字錶法分為對照組和觀察組，各36例。對照組採用三聯療法，觀察組採用序貫療法，比較兩組的臨床治療效果。結果觀察組患者的潰瘍愈閤率及幽門螺桿菌根除率分彆為91.7%、97.2%，明顯高于對照組的72.2%、77.8%，兩組間差異有統計學意義（P＜0.05）；兩組不良反應髮生率分彆為5.6%、11.1%，組間差異無統計學意義（P＞0.05）。結論序貫療法治療幽門螺桿菌暘性潰瘍的臨床療效更佳，具有較高的潰瘍愈閤率及幽門螺桿菌根除率，且安全性好。
목적：비교서관요법화삼련요법치료유문라간균양성궤양적림상료효。방법선택2012년3월-2013년1월진치적유문라간균양성궤양환자72례작위연구대상，안조수궤수자표법분위대조조화관찰조，각36례。대조조채용삼련요법，관찰조채용서관요법，비교량조적림상치료효과。결과관찰조환자적궤양유합솔급유문라간균근제솔분별위91.7%、97.2%，명현고우대조조적72.2%、77.8%，량조간차이유통계학의의（P＜0.05）；량조불량반응발생솔분별위5.6%、11.1%，조간차이무통계학의의（P＞0.05）。결론서관요법치료유문라간균양성궤양적림상료효경가，구유교고적궤양유합솔급유문라간균근제솔，차안전성호。
Objective To compare the effect of sequential therapy and triple therapy for Helicobacter pylori positive ulcers. Methods From March 2012 to January 2013 in the hospital, 72 cases of Helicobacter pylori positive ulcers were selected as subjects of this research, they were randomly divided into the control group and the observation group and 36 cases in each group.The control group treated with triple therapy, the observation group treated with sequential therapy, the clinical effect of two groups were compared. Results The ulcer healing rate and Helicobacter pylori eradication rate of observation group were 91.7%, 97.2%, signiifcantly higher than 72.2%, 77.8%of the control group, the differences were statistically signiifcant between two groups (P<0.05);the adverse reactions of two group were 5.6%, 11.1%, there was no signiifcant difference between two groups (P>0.05). Conclusion Sequential therapy for Helicobacter pylori positive ulcers has better clinical efifcacy, it has a higher rate of ulcer healing and Helicobacter pylori eradication, and good safety.
