湖北科技学院学报（医学版）
湖北科技學院學報（醫學版）
호북과기학원학보（의학판）
JOURNAL OF XIANNING UNIVERSITY (MEDICAL SCIENCES)
2013年
5期
377-379
,共3页
高效液相色谱法%醋酸地塞米松%搽剂%含量测定
高效液相色譜法%醋痠地塞米鬆%搽劑%含量測定
고효액상색보법%작산지새미송%차제%함량측정
HPLC%Dexamethone acetate%Liniment%Content determination
目的：建立醋酸地塞米松搽剂中醋酸地塞米松含量测定的方法。方法高效液相色谱法（ HPLC）测定醋酸地塞米松搽剂中醋酸地塞米松的含量，选用C18（200mm ×4．6mm，5μm）色谱柱，流动相为甲醇-水（80∶
目的：建立醋痠地塞米鬆搽劑中醋痠地塞米鬆含量測定的方法。方法高效液相色譜法（ HPLC）測定醋痠地塞米鬆搽劑中醋痠地塞米鬆的含量，選用C18（200mm ×4．6mm，5μm）色譜柱，流動相為甲醇-水（80∶
목적：건립작산지새미송차제중작산지새미송함량측정적방법。방법고효액상색보법（ HPLC）측정작산지새미송차제중작산지새미송적함량，선용C18（200mm ×4．6mm，5μm）색보주，류동상위갑순-수（80∶
Objective To establish a method for the content determination of dexamethasone acetate lin-iment.Methods The content of dexamethasone acetate in dexamethasone acetate liniment was determined by HPLCwith C18 analytical column(200 ×4.6mm, 5μm).The mobile phase was methanol-water(80∶20), the flow rate was 1ml/min,the the injection volume was20μl and the detectionwavelength was240nm.Results The calibration curve was linear within the concentration range of 20.32~101.60 mg· L -1.The average recovery was 99 .96%( n=5 ) and RSD was 0 .44%.Conclusion The method is simple , rapid and accurate and it is suitable for the determination of dexamethasone acetate liniment .
