CAJ | 학술논문

结直肠癌( Colorectal cancer,CRC)是消化系统的常见恶性肿瘤之一。 MicroRNA家族与CRC的相关基因和通路有着广泛的联系。 MicroRNA家族中有些是促癌基因,有些作为抑癌基因发挥作用,与细胞的各种信号传导通路组成一个复杂的调控网络,随着表达的异常,促进肿瘤的发展。本文综述了MicroRNA家族在结肠癌发生发展过程中的作用。
결직장암( Colorectal cancer,CRC)시소화계통적상견악성종류지일。 MicroRNA가족여CRC적상관기인화통로유착엄범적련계。 MicroRNA가족중유사시촉암기인,유사작위억암기인발휘작용,여세포적각충신호전도통로조성일개복잡적조공망락,수착표체적이상,촉진종류적발전。본문종술료MicroRNA가족재결장암발생발전과정중적작용。
Colorectal cancer is one of the common malignant tumors of the digestive system. There are extensive contacts between MicroRNA family with CRC-related genes and pathways. With the exception of expression,they promote tumor development. This contents summarized that the MicroRNA family's action in the colorectal cancers development and discover.