中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
5期
768-770
,共3页
肾上腺素%机械通气%喉头水肿%雾化吸入
腎上腺素%機械通氣%喉頭水腫%霧化吸入
신상선소%궤계통기%후두수종%무화흡입
adrenaline%mechanical ventilation%laryngeal edema%atomization inhalation
目的：探讨肾上腺素、布地奈德雾化吸入治疗气管插管患儿拔管后喉头水肿的疗效。方法回顾性分析124例重症肺炎行气管插管拔管后出现喉头水肿的患儿，根据拔管后主要治疗方法不同分为A组和B组，A组用氧气雾化吸入肾上腺素治疗喉头水肿，B组用氧气雾化吸入盐酸布地奈德治疗喉头水肿，观察两组喉头水肿症状持续时间、雾化后即刻动脉血气及雾化1h后呼吸频率和心率。结果 A组喉头水肿持续时间为（26．91±12．38） h，B组为（34．86±13．21） h，A组症状持续时间较B组短，两组比较，差异有统计学意义（t＝-2．691，P＜0．05）；A组雾化后即刻动脉血氧分压为（88．57±9．06）mmHg，B组为（76．81±11．03）mmHg，A组动脉血氧分压较B组高，两组比较，差异有统计学意义（t＝2．529， P＜0．05）；A组二氧化碳分压为（41．27±11．50）mmHg，B组为（62．21±11．31）mmHg，A组二氧化碳分压较B组低，两组比较，差异有统计学意义（t＝-5．529，P＜0．05）；雾化1h后A组呼吸频率为（34．32±7．79）次/min，B组为（41．18±7．76）次/min，A组呼吸频率较B组低，两组比较，差异有统计学意义（ t＝-3．899，P＜0．05）。结论氧气雾化吸入肾上腺素可以缩短喉头水肿症状持续时间，提高动脉血氧分压，降低二氧化碳分压，降低呼吸频率。
目的：探討腎上腺素、佈地奈德霧化吸入治療氣管插管患兒拔管後喉頭水腫的療效。方法迴顧性分析124例重癥肺炎行氣管插管拔管後齣現喉頭水腫的患兒，根據拔管後主要治療方法不同分為A組和B組，A組用氧氣霧化吸入腎上腺素治療喉頭水腫，B組用氧氣霧化吸入鹽痠佈地奈德治療喉頭水腫，觀察兩組喉頭水腫癥狀持續時間、霧化後即刻動脈血氣及霧化1h後呼吸頻率和心率。結果 A組喉頭水腫持續時間為（26．91±12．38） h，B組為（34．86±13．21） h，A組癥狀持續時間較B組短，兩組比較，差異有統計學意義（t＝-2．691，P＜0．05）；A組霧化後即刻動脈血氧分壓為（88．57±9．06）mmHg，B組為（76．81±11．03）mmHg，A組動脈血氧分壓較B組高，兩組比較，差異有統計學意義（t＝2．529， P＜0．05）；A組二氧化碳分壓為（41．27±11．50）mmHg，B組為（62．21±11．31）mmHg，A組二氧化碳分壓較B組低，兩組比較，差異有統計學意義（t＝-5．529，P＜0．05）；霧化1h後A組呼吸頻率為（34．32±7．79）次/min，B組為（41．18±7．76）次/min，A組呼吸頻率較B組低，兩組比較，差異有統計學意義（ t＝-3．899，P＜0．05）。結論氧氣霧化吸入腎上腺素可以縮短喉頭水腫癥狀持續時間，提高動脈血氧分壓，降低二氧化碳分壓，降低呼吸頻率。
목적：탐토신상선소、포지내덕무화흡입치료기관삽관환인발관후후두수종적료효。방법회고성분석124례중증폐염행기관삽관발관후출현후두수종적환인，근거발관후주요치료방법불동분위A조화B조，A조용양기무화흡입신상선소치료후두수종，B조용양기무화흡입염산포지내덕치료후두수종，관찰량조후두수종증상지속시간、무화후즉각동맥혈기급무화1h후호흡빈솔화심솔。결과 A조후두수종지속시간위（26．91±12．38） h，B조위（34．86±13．21） h，A조증상지속시간교B조단，량조비교，차이유통계학의의（t＝-2．691，P＜0．05）；A조무화후즉각동맥혈양분압위（88．57±9．06）mmHg，B조위（76．81±11．03）mmHg，A조동맥혈양분압교B조고，량조비교，차이유통계학의의（t＝2．529， P＜0．05）；A조이양화탄분압위（41．27±11．50）mmHg，B조위（62．21±11．31）mmHg，A조이양화탄분압교B조저，량조비교，차이유통계학의의（t＝-5．529，P＜0．05）；무화1h후A조호흡빈솔위（34．32±7．79）차/min，B조위（41．18±7．76）차/min，A조호흡빈솔교B조저，량조비교，차이유통계학의의（ t＝-3．899，P＜0．05）。결론양기무화흡입신상선소가이축단후두수종증상지속시간，제고동맥혈양분압，강저이양화탄분압，강저호흡빈솔。
Objective To evaluate the efficacy of oxygen-driven aerosol inhalation of adrenaline and budesonide on children ’ s laryngeal edema after removing endotracheal intubation .Methods This study was conducted by a retrospective analysis .Totally 124 children with laryngeal edema after removing endotracheal intubation were divided into group A and B according to different treatment methods .Group A was treated by using oxygen-driven aerosol inhalation of adrenaline , while group B was treated by using oxygen-driven aerosol inhalation of budesonide .Evaluation indicators were observed in two groups , including the duration of laryngeal edema , arterial blood gas immediately after finishing atomization inhalation , respiratory rate and heart rate 1h after finishing atomization inhalation .Results The duration of laryngeal edema was 26.91 ±12.38 h and 34.86 ±13.21 h, respectively in group A and group B, and the difference was significant (t=-2.691,P<0.05).The PaO2 monitored immediately after finishing atomization inhalation was 88.57 ±9.06mmHg and 76.81 ±11.03 mmHg, respectively in group A and group B , and the difference was still significant ( t =2.529, P <0.05).The PaCO2 monitored immediately after finishing atomization inhalation in group A (41.27 ±11.50 mmHg) was lower than that in group B (62.21 ±11.31 mmHg) with significant difference (t=-5.529,P<0.05).The respiratory frequency was 34.32 ±7.79 in group A and 41.18 ±7.76 in group B.There was statistical significance in it (t=-3.899, P<0.05).Conclusion Oxygen-driven aerosol inhalation of adrenaline can shorten the duration of laryngeal edema , improve PaO2 , reduce PaCO2 and reduce respiratory frequency .
