中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
5期
740-742
,共3页
几丁糖%补佳乐%宫内节育器%宫腔粘连
幾丁糖%補佳樂%宮內節育器%宮腔粘連
궤정당%보가악%궁내절육기%궁강점련
medical chitosan%estradiol valerate%intrauterine device ( IUD)%intrauterine adhesion ( IUA)
目的：观察几丁糖与补佳乐联合应用在中～重度宫腔粘连术后预防再粘连的效果。方法将68例行宫腔镜下粘连分离术的中、重度宫腔粘连患者做为研究对象，按术后使用防粘连方法的不同随机分成两组。研究组34例，术毕宫腔内放置2％几丁糖3mL及术后口服补佳乐；对照组34例，术毕宫腔放置节育器及口服补佳乐；补佳乐口服方法为2mg/次，2次/日，共21天，疗程为3个月。观察两组术后宫腔形态恢复情况以评定疗效。结果对68例宫内节育器患者术后随访6个月，研究组24例月经恢复正常，对照组20例恢复正常；研究组4例月经量较术前增多，对照组6例；研究组1例仍闭经，对照组3例闭经；两组患者10例术后周期性腹痛症状均消失。研究组总有效率94．11％，对照组总有效率73．53％，两组比较差异有统计学意义（χ2＝5．314，P＜0．05）。结论几丁糖联合补佳乐适合宫腔镜下分离宫腔粘连术后预防宫腔再次粘连。
目的：觀察幾丁糖與補佳樂聯閤應用在中～重度宮腔粘連術後預防再粘連的效果。方法將68例行宮腔鏡下粘連分離術的中、重度宮腔粘連患者做為研究對象，按術後使用防粘連方法的不同隨機分成兩組。研究組34例，術畢宮腔內放置2％幾丁糖3mL及術後口服補佳樂；對照組34例，術畢宮腔放置節育器及口服補佳樂；補佳樂口服方法為2mg/次，2次/日，共21天，療程為3箇月。觀察兩組術後宮腔形態恢複情況以評定療效。結果對68例宮內節育器患者術後隨訪6箇月，研究組24例月經恢複正常，對照組20例恢複正常；研究組4例月經量較術前增多，對照組6例；研究組1例仍閉經，對照組3例閉經；兩組患者10例術後週期性腹痛癥狀均消失。研究組總有效率94．11％，對照組總有效率73．53％，兩組比較差異有統計學意義（χ2＝5．314，P＜0．05）。結論幾丁糖聯閤補佳樂適閤宮腔鏡下分離宮腔粘連術後預防宮腔再次粘連。
목적：관찰궤정당여보가악연합응용재중～중도궁강점련술후예방재점련적효과。방법장68례행궁강경하점련분리술적중、중도궁강점련환자주위연구대상，안술후사용방점련방법적불동수궤분성량조。연구조34례，술필궁강내방치2％궤정당3mL급술후구복보가악；대조조34례，술필궁강방치절육기급구복보가악；보가악구복방법위2mg/차，2차/일，공21천，료정위3개월。관찰량조술후궁강형태회복정황이평정료효。결과대68례궁내절육기환자술후수방6개월，연구조24례월경회복정상，대조조20례회복정상；연구조4례월경량교술전증다，대조조6례；연구조1례잉폐경，대조조3례폐경；량조환자10례술후주기성복통증상균소실。연구조총유효솔94．11％，대조조총유효솔73．53％，량조비교차이유통계학의의（χ2＝5．314，P＜0．05）。결론궤정당연합보가악괄합궁강경하분리궁강점련술후예방궁강재차점련。
Objective To study the effect of medical chitosan and estradiol valerate in preventing adhesion recurrence after transcervical resection of moderate or severe intrauterine adhesions (IUA).Methods Clinical data of 68 patients with moderate or severe IUA who underwent transcervical resection were studied retrospectively .They were divided into two groups according to different therapy methods . Study group (34 patients ) received 2% medical chitosan 3ml in intrauterine cavity and oral administration of estradiol valerate after transcervial resection , while patients in control group were placed with intrauterine device ( IUD) and oral administratin of estradiol valerate after operation with same usage .Estradiol valerate was taken 2mg per time, twice per day for 21 days.The course was 3 months.The restore of intrauterine cavity were studied .Results There were 68 cases of IUD followed up for 6 months after operation .In the study group 24 cases recovered with normal menstruation , while in the control group 20 recovered .There were 4 in the study group and 6 in the control group with much more menstrual blood volume than before .Amenorrhea occurred in 1 case in the study group and 3 cases in the control group.The overall effective rate of the study group and the control group was 94.11% and 73.53%, respectively, and there was significant difference between two groups (χ2 =5.314,P <0.05).Conclusion Infusing medical chitosan and estradiol valerate after transcervical resection is an effective method in preventing adhesion recurrence .
