CAJ | 학술논문

目的：对不同年龄段卵巢功能衰退患者的就诊症状及相关因素进行分析，以更好指导临床工作。方法选取2011年7月至2012年8月就诊于山西医科大学第一医院妇产科门诊，诊断为卵巢功能衰退患者共185例，其中卵巢早衰32例（包括卵巢早衰6例，过渡期卵巢衰竭26例），围绝经期42例，绝经后111例。对患者的一般状况及就诊症状问诊并行绝经症状评分，整理数据资料进行组间比较及影响因素的统计学分析。结果就诊症状卵巢早衰组月经紊乱占第1位（81．3％）；围绝经期组与绝经后组潮热出汗占第1位（71．4％、55．9％）；组间比较，月经紊乱、潮热出汗、失眠、骨关节肌肉痛、心悸差异有统计学意义（χ2值分别为108．130、33．697、11．079、17．600、9．871，均P＜0．05）。绝经症状与年龄、文化程度有相关性（相关系数分别为0．420、0．549，均P＜0．05）。结论主要就诊症状卵巢早衰组为月经紊乱，围绝经期及绝经后组为潮热出汗；绝经后组骨关节肌肉痛发生率高于围绝经期，而卵巢早衰组无此症状；绝经症状随年龄增加而加重，文化程度越低绝经症状越重。
목적：대불동년령단란소공능쇠퇴환자적취진증상급상관인소진행분석，이경호지도림상공작。방법선취2011년7월지2012년8월취진우산서의과대학제일의원부산과문진，진단위란소공능쇠퇴환자공185례，기중란소조쇠32례（포괄란소조쇠6례，과도기란소쇠갈26례），위절경기42례，절경후111례。대환자적일반상황급취진증상문진병행절경증상평분，정리수거자료진행조간비교급영향인소적통계학분석。결과취진증상란소조쇠조월경문란점제1위（81．3％）；위절경기조여절경후조조열출한점제1위（71．4％、55．9％）；조간비교，월경문란、조열출한、실면、골관절기육통、심계차이유통계학의의（χ2치분별위108．130、33．697、11．079、17．600、9．871，균P＜0．05）。절경증상여년령、문화정도유상관성（상관계수분별위0．420、0．549，균P＜0．05）。결론주요취진증상란소조쇠조위월경문란，위절경기급절경후조위조열출한；절경후조골관절기육통발생솔고우위절경기，이란소조쇠조무차증상；절경증상수년령증가이가중，문화정도월저절경증상월중。
Objective To analyze the symptoms and related factors of ovarian failure in patients with different ages for better guidance for clinical work.Methods From July 2011 to August 2012 185 cases were diagnosed with ovarian failure in outpatient department of gynecology and obstetrics in First Clinical Medical College of Shanxi Medical University , including 32 cases of premature ovarian failure (POF) [6 cases of POF and 26 cases of transitional ovarian failure (TOF)], 42 perimenopausal women and 111 postmenopausal cases. The patients’ general situations and treatment symptoms were inquired and menopausal symptoms were graded .The data were collected for comparison among groups and statistical analysis of the influencing factors .Results In POF group the treatment symptoms of menstrual disorders ranked first (81.3%), while in perimenopausal and postmenopausal groups , hot flushes and sweating ranked first (71.4%, 55.9%).Comparison among groups showed that there were statistically significant differences in menstrual disorders , hot flushes and sweating, insomnia, bone, joint and muscle pain, and heart palpitations (χ2 values was 108.130, 33.697, 11.079, 17.600 and 9.871, respectively, all P<0.05).Menopausal symptoms were associated with age and education level (coefficient correlation was 0.420 and 0.549, respectively, both P<0.05).Conclusion The main treatment symptoms of the group of POF is menstrual disorders , and hot flushes and sweating are the main treatment symptoms of perimenopausal group and postmenopausal group .The incidence of bone , joint and muscle pain is higher in postmenopausal group than perimenopausal group , but it is not found in the group of POF .Menopausal symptoms increase with age , and the lower education level , the severer menopausal symptoms .