中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
5期
735-737
,共3页
宫颈上皮内瘤变%环形电切术术%冷刀锥切术%临床疗效
宮頸上皮內瘤變%環形電切術術%冷刀錐切術%臨床療效
궁경상피내류변%배형전절술술%냉도추절술%림상료효
cervical intraepithelial neoplasia (CIN)%loop electrosurgical excision procedure (LEEP)%cold-knife conization (CKC)%clinical effects
目的：比较环形电切术（ LEEP）与冷刀锥切术（ CKC）治疗宫颈上皮内瘤变Ⅲ级（ CIN Ⅲ）的临床疗效。方法将65例CINⅢ级患者随机分为LEEP组（33例）和CKC组（32例）。术后随访1～9个月，比较两组的痊愈率、手术时间、术中出血量以及术后并发症情况。结果 LEEP组与CKC组的痊愈率分别为97．0％（32/33）和93．8％（30/32），两组比较无显著性差异（P＞0．05）。 LEEP组的手术时间和术中出血量分别为（7．9±3．4）分钟和（10．2±3．1）mL，显著少于CKC组（t值分别为19．774、20．131，均P＜0．05）。两组的术后并发症（术后出血、宫颈粘连、盆腔感染、下腹部胀痛）发生率比较均无显著性差异（均P＞0．05）。结论 LEEP术治疗CINⅢ的手术创伤小、治愈率高，是治疗该疾病的理想方法。
目的：比較環形電切術（ LEEP）與冷刀錐切術（ CKC）治療宮頸上皮內瘤變Ⅲ級（ CIN Ⅲ）的臨床療效。方法將65例CINⅢ級患者隨機分為LEEP組（33例）和CKC組（32例）。術後隨訪1～9箇月，比較兩組的痊愈率、手術時間、術中齣血量以及術後併髮癥情況。結果 LEEP組與CKC組的痊愈率分彆為97．0％（32/33）和93．8％（30/32），兩組比較無顯著性差異（P＞0．05）。 LEEP組的手術時間和術中齣血量分彆為（7．9±3．4）分鐘和（10．2±3．1）mL，顯著少于CKC組（t值分彆為19．774、20．131，均P＜0．05）。兩組的術後併髮癥（術後齣血、宮頸粘連、盆腔感染、下腹部脹痛）髮生率比較均無顯著性差異（均P＞0．05）。結論 LEEP術治療CINⅢ的手術創傷小、治愈率高，是治療該疾病的理想方法。
목적：비교배형전절술（ LEEP）여냉도추절술（ CKC）치료궁경상피내류변Ⅲ급（ CIN Ⅲ）적림상료효。방법장65례CINⅢ급환자수궤분위LEEP조（33례）화CKC조（32례）。술후수방1～9개월，비교량조적전유솔、수술시간、술중출혈량이급술후병발증정황。결과 LEEP조여CKC조적전유솔분별위97．0％（32/33）화93．8％（30/32），량조비교무현저성차이（P＞0．05）。 LEEP조적수술시간화술중출혈량분별위（7．9±3．4）분종화（10．2±3．1）mL，현저소우CKC조（t치분별위19．774、20．131，균P＜0．05）。량조적술후병발증（술후출혈、궁경점련、분강감염、하복부창통）발생솔비교균무현저성차이（균P＞0．05）。결론 LEEP술치료CINⅢ적수술창상소、치유솔고，시치료해질병적이상방법。
Objective To compare the clinical effects of loop electrosurgical excision procedure ( LEEP) and cold-knife conization ( CKC) in the treatment of cervical intraepithelial neoplasia Ⅲ ( CINⅢ) .Methods Sixty-five patients with CINⅢ were randomly divided into LEEP group (n=33) and CKC group (n=32).After following up for 1-9 months, the cure rate, operation time, intraoperative blood loss and postoperative complications were observed and compared between two groups .Results The cure rate of LEEP group and CKC group was 97.0%(32/33)and 93.8%(30/32), respectively, and there was no significant difference between two groups (P>0.05).The operation time and intraoperative blood loss of LEEP group was 7.9 ±3.4min and 10.2 ±3.1mL, respectively, which was significantly less than CKC group (t value was 19.774 and 20.131, respectively, both P <0.05).The difference in the incidence rate of postoperative complications ( such as postoperative bleeding , cervical adherence , pelvic cavity infection and lower abdominal pain ) was not significant between two groups(all P>0.05).Conclusion The operative wound is small and cure rate is high with LEEP .LEEP is an ideal way to treat CIN Ⅲ.
