中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
5期
687-688,689
,共3页
小儿肺炎%支原体肺炎%阿奇霉素%痰热清
小兒肺炎%支原體肺炎%阿奇黴素%痰熱清
소인폐염%지원체폐염%아기매소%담열청
pneumonia%mycoplasma pneumonia%azithromycin%Tanreqing
目的：探讨阿奇霉素联合痰热清治疗小儿肺炎支原体肺炎的临床疗效。方法将2010年1月至2011年12月入住余杭区第一人民医院儿科确诊肺炎支原体肺炎的患儿98例按就诊顺序分为两组，对照组选用阿奇霉素序贯疗法，观察组采用阿奇霉素和痰热清联合治疗，两组各治疗1个疗程后观察患儿临床疗效。结果观察组总有效率为98．0％；对照组总有效率为83．7％，两组总有效率比较差异有统计学意义（χ2＝7．85，P＜0．05）。观察组咳嗽消失时间、体温恢复正常时间、干湿罗音消失时间均低于对照组，两组比较差异均有统计学意义（t值分别为10．85、12．92、9．88，均P＜0．01）。观察组不良反应1例，占2．0％，对照组不良反应6例，占12．2％，两组不良反应发生率比较差异有统计学意义（χ2＝2．84，P＜0．05）。结论阿奇霉素与痰热清联合应用治疗小儿肺炎支原体肺炎，临床效果显著，可有效改善患者各方面临床症状和体征，毒副作用小，并可大大缩短病程，避免并发症的发生，具有积极的临床意义。
目的：探討阿奇黴素聯閤痰熱清治療小兒肺炎支原體肺炎的臨床療效。方法將2010年1月至2011年12月入住餘杭區第一人民醫院兒科確診肺炎支原體肺炎的患兒98例按就診順序分為兩組，對照組選用阿奇黴素序貫療法，觀察組採用阿奇黴素和痰熱清聯閤治療，兩組各治療1箇療程後觀察患兒臨床療效。結果觀察組總有效率為98．0％；對照組總有效率為83．7％，兩組總有效率比較差異有統計學意義（χ2＝7．85，P＜0．05）。觀察組咳嗽消失時間、體溫恢複正常時間、榦濕囉音消失時間均低于對照組，兩組比較差異均有統計學意義（t值分彆為10．85、12．92、9．88，均P＜0．01）。觀察組不良反應1例，佔2．0％，對照組不良反應6例，佔12．2％，兩組不良反應髮生率比較差異有統計學意義（χ2＝2．84，P＜0．05）。結論阿奇黴素與痰熱清聯閤應用治療小兒肺炎支原體肺炎，臨床效果顯著，可有效改善患者各方麵臨床癥狀和體徵，毒副作用小，併可大大縮短病程，避免併髮癥的髮生，具有積極的臨床意義。
목적：탐토아기매소연합담열청치료소인폐염지원체폐염적림상료효。방법장2010년1월지2011년12월입주여항구제일인민의원인과학진폐염지원체폐염적환인98례안취진순서분위량조，대조조선용아기매소서관요법，관찰조채용아기매소화담열청연합치료，량조각치료1개료정후관찰환인림상료효。결과관찰조총유효솔위98．0％；대조조총유효솔위83．7％，량조총유효솔비교차이유통계학의의（χ2＝7．85，P＜0．05）。관찰조해수소실시간、체온회복정상시간、간습라음소실시간균저우대조조，량조비교차이균유통계학의의（t치분별위10．85、12．92、9．88，균P＜0．01）。관찰조불량반응1례，점2．0％，대조조불량반응6례，점12．2％，량조불량반응발생솔비교차이유통계학의의（χ2＝2．84，P＜0．05）。결론아기매소여담열청연합응용치료소인폐염지원체폐염，림상효과현저，가유효개선환자각방면림상증상화체정，독부작용소，병가대대축단병정，피면병발증적발생，구유적겁적림상의의。
Objective To explore the clinical efficacy of azithromycin combined with Tanreqing in the treatment of mycoplasma pneumoniae pneumonia .Methods Totally 98 cases were diagnosed with mycoplasma pneumonia in the First People ’ s Hospital of Yuhang District in the period of January 2010 to December 2011.They were divided into two groups according to diagnosis order .The control group was treated with azithromycin sequential therapy , while the observation group accepted azithromycin combined with Tanreqing .After one course of treatment clinical efficacy of two groups was observed .Results The total effective rate was 98.0%in the observation group and 83.7%in the control group.The total effective rate was significantly different (χ2 =7.85, P<0.05).Disappearance of cough, body temperature returning to normal , wet and dry rales disappearance were earlier in the observation group than the control group , and the differences were statistically significant (t value was 10.85, 12.92 and 9.88, respectively, all P<0.01).Adverse reactions occurred in 1 case (2.0%) in the observation group and in 6 cases (12.2%) in the control group .The difference in the incidence of adverse reactions was statistically different (χ2 =2.84,P<0.05).Conclusion Azithromycin combined with Tanreqing is effective in treatment of mycoplasma pneumoniae pneumonia , and can effectively improve all aspects of patient clinical signs and symptoms .The side effects are mild .It can greatly shorten course of disease and avoid complications with positive clinical significance .
