CAJ | 학술논문

目的：分析C反应蛋白(CRP)、白细胞(WBC)和纤维蛋白原(FIB)在6种疾病中血液水平的均值、阳性检出率和相关性。方法：检测6种疾病148例患者血液中的CRP、WBC和FIB含量，分病种对检测结果作出统计分析。结果：CRP、WBC和FIB的血液水平在细菌性肺炎、糖尿病、高血压病、骨关节炎、骨折和腰椎间盘突出症均有升高的病例，但以细菌性肺炎均值升高和阳性检出率居多比较明显，其他5种非感染性疾病均值升高和阳性检出率居多以CRP为主；3项指标在5种非感染性疾病与细菌性肺炎之间有差异，而相互比较差异无统计学意义；3项指标在大多数疾病中相关性较差，仅在骨折病例中相关性较好。结论：多种疾病可使CRP、WBC和FIB的血液水平发生变化，且以感染性疾病更为明显，CRP是炎症反应最有代表性的指标之一。
목적：분석C반응단백(CRP)、백세포(WBC)화섬유단백원(FIB)재6충질병중혈액수평적균치、양성검출솔화상관성。방법：검측6충질병148례환자혈액중적CRP、WBC화FIB함량，분병충대검측결과작출통계분석。결과：CRP、WBC화FIB적혈액수평재세균성폐염、당뇨병、고혈압병、골관절염、골절화요추간반돌출증균유승고적병례，단이세균성폐염균치승고화양성검출솔거다비교명현，기타5충비감염성질병균치승고화양성검출솔거다이CRP위주；3항지표재5충비감염성질병여세균성폐염지간유차이，이상호비교차이무통계학의의；3항지표재대다수질병중상관성교차，부재골절병례중상관성교호。결론：다충질병가사CRP、WBC화FIB적혈액수평발생변화，차이감염성질병경위명현，CRP시염증반응최유대표성적지표지일。
Objective:To analyze the mean value,positive detection rate and correlation for the blood levels of C-reactive protein(CRP),white blood cells(WBC) and fibrinogen(FIB).Method:The contents of CRP,WBC and FIB were detected in 148 cases for 6 kinds of diseases.The detected results were making the statistics according to the disease kinds.Result:The elevated blood levels of CRP,WBC and FIB all had cases in the bacterial pneumonia,diabetes mellitus, hypertension,osteoarthritis,fracture and slipped lumbar intervertebral disc,but the elevated mean value and increased positive detection rate were comparatively obvious for the bacterial pneumonia.The elevated mean value and increased positive detection rate were mainly in CRP for 5 kinds non infectious diseases.3 item indexes had some differences in 5 kinds non infectious diseases compared with bacterial pneumonia,but had no differences compared with each other.The correlation of 3 item indexes were relatively poor in most diseases and the correlation was better only in fracture.Conclusion:The multiple diseases may change the blood levels of CRP,WBC and FIB and these are more obvious in infectious diseases.CRP is one of the most representative indexes for the inflammatory reaction.