CAJ | 학술논문

目的：探讨并比较局部使用盐酸米诺环素和10%碘合剂治疗种植体周围炎患者的临床疗效和安全性。方法将60例种植体周围炎患者随机分为对照组和观察组,每组30例,对照组患者给予10%碘合剂牙周留置,观察组给予盐酸米诺环素进行治疗,3周为1个疗程,统计患者在治疗前后菌斑指数( PLI)、探诊深度( PD)和龈沟出血指数( SBI)的变化情况。结果治疗1、3周后,两组患者的PLI、PD、SBI均明显降低,差异有统计学意义(P<0．05)。治疗3周后变化最为明显,观察组、对照组的PLI分别为(1．46±0．31)、(1．62±0．35),PD分别为(2．76±0．35) mm、(3．12±0．41) mm,两组比较差异均有统计学意义(P<0．05)。6周后各指标均有上升。对照组和观察组的不良反应发生率分别为3．3%、3．2%,两组比较差异无统计学意义( P>0．05)。结论盐酸米诺环素治疗种植体周围炎的疗效优于10%碘合剂,安全性高,但应每隔3周进行重复治疗,有利于种植体周围炎的彻底治愈。
목적：탐토병비교국부사용염산미낙배소화10%전합제치료충식체주위염환자적림상료효화안전성。방법장60례충식체주위염환자수궤분위대조조화관찰조,매조30례,대조조환자급여10%전합제아주류치,관찰조급여염산미낙배소진행치료,3주위1개료정,통계환자재치료전후균반지수( PLI)、탐진심도( PD)화간구출혈지수( SBI)적변화정황。결과치료1、3주후,량조환자적PLI、PD、SBI균명현강저,차이유통계학의의(P<0．05)。치료3주후변화최위명현,관찰조、대조조적PLI분별위(1．46±0．31)、(1．62±0．35),PD분별위(2．76±0．35) mm、(3．12±0．41) mm,량조비교차이균유통계학의의(P<0．05)。6주후각지표균유상승。대조조화관찰조적불량반응발생솔분별위3．3%、3．2%,량조비교차이무통계학의의( P>0．05)。결론염산미낙배소치료충식체주위염적료효우우10%전합제,안전성고,단응매격3주진행중복치료,유리우충식체주위염적철저치유。
Objective To compare the clinical efficacy of local application of periocline and 10% iodine mix-ture on peri-implantitis. Methods 60 patients with peri-implantitis were randomly divided into observation group and control group. Patients in control group(n=30) were given 10% iodine mixture once a week,patients in observation group were given periocline,all the patients were treated for 3 weeks. The PLI,SBI and PD of the patients were meas-ured at the beginning of the treatment and after treatment. Results The PLI,SBI and PD of the two groups decreased significantly at 1 and 3 weeks after treatment(P<0. 05),the changes at 3 weeks after treatment were the most remarka-ble,the PLI of observation group and control group were (1. 46 ± 0. 31) and (1. 62 ± 0. 35),and the PD were(2. 76 ± 0. 35) mm and(3. 12 ± 0. 41) mm respectively,there were significant differences between the two groups(P<0. 05). The above indexes at 6 weeks after treatment increased. The incidence of adverse reactions in control group and obser-vation group were 3. 3% and 3. 2% respectively, there was no significant difference between the two groups ( P >0. 05). Conclusion The curative effect of periocline for peri-implantitis is better than 10% iodine agent with highly safety,and the treatment should be repeated every 3 weeks for a lasting effect,it is benefit for peri-implantitis.