中国医学前沿杂志(电子版)
中國醫學前沿雜誌(電子版)
중국의학전연잡지(전자판)
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
4期
45-48
,共4页
凌秀兰%钟宝雁%洪敬丹%赖雪%黄珊珊
凌秀蘭%鐘寶雁%洪敬丹%賴雪%黃珊珊
릉수란%종보안%홍경단%뢰설%황산산
卡前列素氨丁三醇%米索前列醇%前置胎盘%产后出血
卡前列素氨丁三醇%米索前列醇%前置胎盤%產後齣血
잡전렬소안정삼순%미색전렬순%전치태반%산후출혈
Hemabate%Misoprostol%Placenta previa%Hemorrhage after cesarean section
目的:观察卡前列素氨丁三醇和米索前列醇在预防前置胎盘产后出血中的临床效果。方法选择在本院行剖宫产手术的前置胎盘孕妇70例,随机分为观察组和对照组,各35例。其中观察组35例采用子宫体注射卡前列素氨丁三醇250μg,对照组采用子宫体注射缩宫素20 U并米索前列醇400μg术后塞肛,两组同时均给予缩宫素20 U静脉点滴维持。比较两组产妇产后出血率、产后2小时及24小时平均出血量,同时观察有无胃肠道不良反应。结果对照组产妇产后出血率为74.3%(16例),产后2小时平均出血量为(433.57±83.7)ml,产后24小时平均出血量为(507.59±80.3)ml;观察组产妇产后出血率为14.3%(5例),产后2小时平均出血量为(271.23±50.4)ml,产后24小时平均出血量为(381.76±78.5)ml,观察组产妇产后2小时及24小时的出血量较对照组明显减少,经统计分析两组间数据比较差异具有显著性(P<0.05);两组间不良反应发生率差异无显著性(P>0.05)。结论卡前列素氨丁三醇预防前置胎盘产后出血疗效优于米索前列醇,建议临床推广应用。
目的:觀察卡前列素氨丁三醇和米索前列醇在預防前置胎盤產後齣血中的臨床效果。方法選擇在本院行剖宮產手術的前置胎盤孕婦70例,隨機分為觀察組和對照組,各35例。其中觀察組35例採用子宮體註射卡前列素氨丁三醇250μg,對照組採用子宮體註射縮宮素20 U併米索前列醇400μg術後塞肛,兩組同時均給予縮宮素20 U靜脈點滴維持。比較兩組產婦產後齣血率、產後2小時及24小時平均齣血量,同時觀察有無胃腸道不良反應。結果對照組產婦產後齣血率為74.3%(16例),產後2小時平均齣血量為(433.57±83.7)ml,產後24小時平均齣血量為(507.59±80.3)ml;觀察組產婦產後齣血率為14.3%(5例),產後2小時平均齣血量為(271.23±50.4)ml,產後24小時平均齣血量為(381.76±78.5)ml,觀察組產婦產後2小時及24小時的齣血量較對照組明顯減少,經統計分析兩組間數據比較差異具有顯著性(P<0.05);兩組間不良反應髮生率差異無顯著性(P>0.05)。結論卡前列素氨丁三醇預防前置胎盤產後齣血療效優于米索前列醇,建議臨床推廣應用。
목적:관찰잡전렬소안정삼순화미색전렬순재예방전치태반산후출혈중적림상효과。방법선택재본원행부궁산수술적전치태반잉부70례,수궤분위관찰조화대조조,각35례。기중관찰조35례채용자궁체주사잡전렬소안정삼순250μg,대조조채용자궁체주사축궁소20 U병미색전렬순400μg술후새항,량조동시균급여축궁소20 U정맥점적유지。비교량조산부산후출혈솔、산후2소시급24소시평균출혈량,동시관찰유무위장도불량반응。결과대조조산부산후출혈솔위74.3%(16례),산후2소시평균출혈량위(433.57±83.7)ml,산후24소시평균출혈량위(507.59±80.3)ml;관찰조산부산후출혈솔위14.3%(5례),산후2소시평균출혈량위(271.23±50.4)ml,산후24소시평균출혈량위(381.76±78.5)ml,관찰조산부산후2소시급24소시적출혈량교대조조명현감소,경통계분석량조간수거비교차이구유현저성(P<0.05);량조간불량반응발생솔차이무현저성(P>0.05)。결론잡전렬소안정삼순예방전치태반산후출혈료효우우미색전렬순,건의림상추엄응용。
Objective To observe the clinical effect of hemabate and misoprostol for preventing postpartum hemorrhage after cesarean section of pregnant women with placenta previa. Methods Selected 70 patients of cesarean section with placenta previa and andomly divided into two groups:treatment group and control group. Control group was injected oxytocin 20 U into their uterine corpus immediately after cesarean section and misoprostol 0.4 mg po, treatment group was injected hemabate 250 μg, then the two groups all were injected oxytocin 20 U by intravenous drip continuously. Then compared the bleeding rate,the bleeding amounts of 2 hours and 24 hours after operation. Results The control group’s bleeding rate was 74.3%, the bleeding amounts of 2 hours was (433.57±83.7) ml and 24 hours was (507.59±80.3) ml;The treatment group’s bleeding rate was 14.3%, the bleeding amounts of 2 hours was (271.23±50.4) ml and 24 hours was (381.76±78.5) ml. The data is statistically signiifcant. Conclusion Hemabate is more effective than misoprostol for preventing postpartum hemorrhage after cesarean section of women with placenta previa.