中国药师
中國藥師
중국약사
CHINA PHARMACIST
2014年
4期
695-696,697
,共3页
延胡索%丹参%提取工艺%正交试验%高效液相色谱法
延鬍索%丹參%提取工藝%正交試驗%高效液相色譜法
연호색%단삼%제취공예%정교시험%고효액상색보법
Rhizoma Corydalis%Salvia miltiorrhiza%Extraction process%Orthogonal test%HPLC
目的：研究乙醇提取延胡索及丹参的最佳工艺,以及考察药材的粉碎度对有效成分的影响。方法：以乙醇浓度、加量、提取时间及提取次数为考察因素,采用L9(34)正交表设计进行正交试验,以延胡索乙素、丹酚酸B的含量为考察指标,优选最佳提取工艺。结果：最佳工艺为延胡索粉碎成最粗粉,6倍量75%乙醇,提取2次,每次1.5 h。结论：该工艺简单、可行,可以用于大规模生产。
目的：研究乙醇提取延鬍索及丹參的最佳工藝,以及攷察藥材的粉碎度對有效成分的影響。方法：以乙醇濃度、加量、提取時間及提取次數為攷察因素,採用L9(34)正交錶設計進行正交試驗,以延鬍索乙素、丹酚痠B的含量為攷察指標,優選最佳提取工藝。結果：最佳工藝為延鬍索粉碎成最粗粉,6倍量75%乙醇,提取2次,每次1.5 h。結論：該工藝簡單、可行,可以用于大規模生產。
목적：연구을순제취연호색급단삼적최가공예,이급고찰약재적분쇄도대유효성분적영향。방법：이을순농도、가량、제취시간급제취차수위고찰인소,채용L9(34)정교표설계진행정교시험,이연호색을소、단분산B적함량위고찰지표,우선최가제취공예。결과：최가공예위연호색분쇄성최조분,6배량75%을순,제취2차,매차1.5 h。결론：해공예간단、가행,가이용우대규모생산。
Objective:To optimize the ethanol extraction process of Rhizoma Corydalis and Salvia miltiorrhiza, and study the effect of comminution degree of the medicinal materials on the effective constituent. Methods:Using the alcohol concentration, alcohol vol-ume, extraction time and extraction times as the impacting factors,the content of tetrahydropalmatine and salvianolic acid as the indi-ces, the extraction process was optimized by orthogonal test of L9(34). Results:The best extraction conditions were as follows:Rhizo-ma Corydalis was crushed into coarse powder, the material / liquid ratio was 1∶6 with 75% ethanol as the extraction solvent,extracting twice with 1. 5h each. Conclusion:The extraction method is appropriate and simple,and can be used in the industrial production.
