CAJ | 학술논문

目的：研究大株红景天对急性冠脉综合征(ACS)患者心功能的影响。方法：将本院2012年2月-2013年2月收住院的120例ACS患者随机分为A组(常规治疗组)和B组(大株红景天治疗组),每组为60例。A组给与ACS的常规治疗如：阿司匹林、氯吡格雷、低分子肝素等,B组患者在常规治疗基础上给与大株红景天注射液10ml静脉点滴7天,每日1次。观察两组患者用药7天前后心功能指标的变化,研究大株红景天注射液对心功能的影响。结果：A、B两组患者经治疗后,血浆脑钠肽前体(NT-proBNP)、心脏射血分数(EF值)均有明显改善(P=0.000),但B组较A组NT-proBNP减低更显著(P<0.001),EF值提高更明显(P<0.009)。结论：在常规治疗基础上加用大株红景天注射液治疗ACS,可更明显降低血浆NT-proBNP水平、提高心脏EF值。大株红景天注射液可明显改善ACS患者的心功能。
목적：연구대주홍경천대급성관맥종합정(ACS)환자심공능적영향。방법：장본원2012년2월-2013년2월수주원적120례ACS환자수궤분위A조(상규치료조)화B조(대주홍경천치료조),매조위60례。A조급여ACS적상규치료여：아사필림、록필격뢰、저분자간소등,B조환자재상규치료기출상급여대주홍경천주사액10ml정맥점적7천,매일1차。관찰량조환자용약7천전후심공능지표적변화,연구대주홍경천주사액대심공능적영향。결과：A、B량조환자경치료후,혈장뇌납태전체(NT-proBNP)、심장사혈분수(EF치)균유명현개선(P=0.000),단B조교A조NT-proBNP감저경현저(P<0.001),EF치제고경명현(P<0.009)。결론：재상규치료기출상가용대주홍경천주사액치료ACS,가경명현강저혈장NT-proBNP수평、제고심장EF치。대주홍경천주사액가명현개선ACS환자적심공능。
Objective:To study the effect of Rhodiola Crenulate injection on the cardiac function in patients with ACS. Methods:120 ACS cases were randomly divided into 2 groups(A group:conventional group and B group:Rhodiola Crenulate group)and were observed the changes of serum NT-proBNP and the heart EF after treating 7 days. A group were given ACS conventional treating methods such as Aspirin,βblockers, clopidogrel, low molecular weight heparin (LMWH). B group were were given Rhodiola Crenulate injection 10ml each day.Results:After treating 7 days, the serum NT-proBNP and the heart EF of two groups were significantly improved(P=0.000),And the B group was better than the A group(P<0.001).Conclusion:Using Rhodiola Crenulate injection treating ACS based on the conventional treatment can obviously increase cardiac function, and is better than the conventional treatment.