CAJ | 학술논문

目的：探讨甲泼尼龙治疗重症急性胰腺炎(SAP)的疗效。方法：将本院152例SAP患者随机分成观察组(76例)与对照组(76例),对照组采用常规治疗,观察组在常规治疗基础上给予甲泼尼龙。结果：观察组患者腹痛缓解时间、血尿淀粉酶恢复时间、腹水消退时间、住院时间、并发症发生率及病死率均明显优于对照组,各项相互比较,P<0.05,均有显著性差异,有统计学意义。观察组患者心、肝、肾功能不全恢复时间与对照组比较,P>0.05,不存在统计学意义。结论：SAP患者采用常规治疗联合甲泼尼龙,其疗效显著、安全可靠、病死率低、并发症少及住院时间短等优点。
목적：탐토갑발니룡치료중증급성이선염(SAP)적료효。방법：장본원152례SAP환자수궤분성관찰조(76례)여대조조(76례),대조조채용상규치료,관찰조재상규치료기출상급여갑발니룡。결과：관찰조환자복통완해시간、혈뇨정분매회복시간、복수소퇴시간、주원시간、병발증발생솔급병사솔균명현우우대조조,각항상호비교,P<0.05,균유현저성차이,유통계학의의。관찰조환자심、간、신공능불전회복시간여대조조비교,P>0.05,불존재통계학의의。결론：SAP환자채용상규치료연합갑발니룡,기료효현저、안전가고、병사솔저、병발증소급주원시간단등우점。
Objective:The objective was to investigate the effects of methylprednisolone on the treatment of severe acute pancreatitis (SAP).Methods:152 cases of SAP patients in the present hospital were randomly divided into the observation group (76 cases) and the control group (76 cases). The control group was conducted conventional therapy, based on which the observation group was further given methylprednisolone treatment.Results:Abdominal pain relief time,hematuria amylase recovery time, ascites subsiding time, hospitalization time, complication rate and case fatality rate of the patients in the observation group were significantly better than that of the control group.There were significant differences and statistical significances between the two groups in mutual comparisons (P<0.05). There was no difference and statistical significance in the incomplete recovery times of the functions of heart,liver,kidney in the patients from the observation group and the control group (P>0.05).Conclusion:There were various advantages including significant treatment effects,safety and reliability, low mortality rate, fewer complications and shorter hospitalization time for the treatment of the SAP patients with the routine therapy combined with methylprednisolone.