CAJ | 학술논문

目的：分析研究阻塞性睡眠呼吸暂停综合征患者血清微量元素及氧化应激指标的变化情况。方法：选取2011年11月~2013年3月于本院进行诊治的54例阻塞性睡眠呼吸暂停综合征患者为观察组,同时期的54名健康人员为对照组,然后将两组人员的血清微量元素及氧化应激指标进行检测及比较,并将观察组中不同严重程度者的上述方面的水平进行比较。结果：观察组的血清Zn、Ca均低于对照组,Cu高于对照组,而血清CAT、TAC、SOD均低于对照组,MDA及LPO则高于对照组,且观察组中重度患者的变化明显大于轻度与中度患者,P均＜0.05,均有显著性差异。结论：阻塞性睡眠呼吸暂停综合征患者血清微量元素及氧化应激指标的变化明显,且受严重程度的影响较大。
목적：분석연구조새성수면호흡잠정종합정환자혈청미량원소급양화응격지표적변화정황。방법：선취2011년11월~2013년3월우본원진행진치적54례조새성수면호흡잠정종합정환자위관찰조,동시기적54명건강인원위대조조,연후장량조인원적혈청미량원소급양화응격지표진행검측급비교,병장관찰조중불동엄중정도자적상술방면적수평진행비교。결과：관찰조적혈청Zn、Ca균저우대조조,Cu고우대조조,이혈청CAT、TAC、SOD균저우대조조,MDA급LPO칙고우대조조,차관찰조중중도환자적변화명현대우경도여중도환자,P균＜0.05,균유현저성차이。결론：조새성수면호흡잠정종합정환자혈청미량원소급양화응격지표적변화명현,차수엄중정도적영향교대。
Objective:To analyze the change situation of serum trace element and oxidative stress indexes of patients with obstructive sleep apnea syndrome.Methods:54 patients with obstructive sleep apnea syndrome who were diagnosed and treated in our hospital from November 2011 to March 2013 were selected as observation group,54 health personal at the same time were selected as control group,then the serum trace element and oxidative stress indexes of two groups were detected and compared,and those indexes levels of observation group with different severity were compared too.Results:The serum Zn and Ca of observation group were both lower than those of control group,Cu was higher than that of control group,serum CAT,TAC and SOD were all lower than those of control group,MDA and LPO were higher than those of control group,and those indexes change of observation group with severe disease were all bigger than those with mild and moderate disease,all P<0.05,there were all significant differences.Conclusion:The change of serum trace element and oxidative stress indexes of patients with obstructive sleep apnea syndrome is obvious,and the influence by the severity of disease is bigger.