CAJ | 학술논문

目的：观察甲氨蝶呤(MTX)联合桂枝茯苓胶囊治疗异位妊娠的效果。方法85例异位妊娠患者随机分成两组,观察组(n=43)给予MTX50mg/m2单次肌内注射,同时加服桂枝茯苓胶囊3粒,3次/d,共4周；对照组(n=42)给予MTX50mg/m2单次肌内注射。观察两组疗效及不良反应情况。结果观察组治疗成功38例(88.3%)；对照组治疗成功34例(81.0%),两组治疗成功率比较无明显差异(P>0.05)。观察组血β-HCG转阴所需时间明显短于对照组(P<0.05),平均住院天数与附件包块消失时间明显少于对照组(P<0.01)。观察组患者输卵管再通率高于对照组(P<0.05)。结论 MTX联合桂枝茯苓胶囊治疗异位妊娠,能促进血β-HCG下降,缩短了住院天数,并且很好的保留了患者的生育功能,是一种较好的保守治疗方法。
목적：관찰갑안접령(MTX)연합계지복령효낭치료이위임신적효과。방법85례이위임신환자수궤분성량조,관찰조(n=43)급여MTX50mg/m2단차기내주사,동시가복계지복령효낭3립,3차/d,공4주；대조조(n=42)급여MTX50mg/m2단차기내주사。관찰량조료효급불량반응정황。결과관찰조치료성공38례(88.3%)；대조조치료성공34례(81.0%),량조치료성공솔비교무명현차이(P>0.05)。관찰조혈β-HCG전음소수시간명현단우대조조(P<0.05),평균주원천수여부건포괴소실시간명현소우대조조(P<0.01)。관찰조환자수란관재통솔고우대조조(P<0.05)。결론 MTX연합계지복령효낭치료이위임신,능촉진혈β-HCG하강,축단료주원천수,병차흔호적보류료환자적생육공능,시일충교호적보수치료방법。
Objective To observe methotrexate (MTX) combined with Gui Zhi Fu Ling mass for the treatment of ectopic pregnancy. Methods 85 patients with ectopic pregnancy were randomly divided into two groups, observation group (n=43) give MTX 50 mg/m2 single intramuscular injection, add Gui Zhi Fu Ling 3 pills at the same time, 3 times/d, a total of four weeks. The control group (n=42) give MTX 50 mg/m 2 single intramuscular injection. Observe two groups of curative effect and adverse reactions. Results For successful treatment group 38 cases (88.3%), successful treatment control group of 34 cases (81.0%) , two groups of treatment successrate was no significant difference (P>0.05). The time needed for turn blood beat HCG observation group was obviously shorter than control group (P<0.05), the average hospitslization days and the accessory bag piece disappear time significantly less than the control group (P<0.01). Observation group of patient with tubal rate is higher than the control group (P<0.05). Conclusion MTX combined Gui Zhi Fu Ling mass in the treatment of ectopic pregnancy, can promote blood beta HCG drops, shorten the hospitalization days, and well keep reproductive function in patients with conservative treatment, so it is a good method.