CAJ | 학술논문

前列腺癌作为男性生殖系统好发的恶性肿瘤,其发生及预后的判断直接关系到男性的生存健康。传统的前列腺癌预后评价指标,如TNM分期、Gleason评分和PSA表达水平等,对临床预后判断有一定意义。但近些年大量分子标志物的发现和应用为前列腺癌的预后评估提供了更可靠、更准确的依据。文章对与前列腺癌发生、转移及血管生成等相关的分子标志物作一综述。
전렬선암작위남성생식계통호발적악성종류,기발생급예후적판단직접관계도남성적생존건강。전통적전렬선암예후평개지표,여TNM분기、Gleason평분화PSA표체수평등,대림상예후판단유일정의의。단근사년대량분자표지물적발현화응용위전렬선암적예후평고제공료경가고、경준학적의거。문장대여전렬선암발생、전이급혈관생성등상관적분자표지물작일종술。
Prostate cancer is the male reproductive system usual malignant tumor,the occurrence and prognosis is directly related to the male survival and health.The traditional prostate cancer prognosis evaluation indicators,such as TNM stage,Gleason score and PSA expression levels,have some significance in clinical.But in recent years,the discovery and application of many molecular markers for prostate cancer prognosis assessment provides more reliable,more accurate basis.Now the occurrence,metastasis and angiogenesis related molecular markers of prostate cancer are reviewed in this paper.