国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
6期
775-778
,共4页
眶下神经阻滞%布比卡因%吗啡%唇裂修复%小儿
眶下神經阻滯%佈比卡因%嗎啡%脣裂脩複%小兒
광하신경조체%포비잡인%마배%진렬수복%소인
Infraorbital nerve block%Bupivacaine%Morphine%Cleft lip repair%Children
目的 观察布比卡因复合吗啡注射液应用于眶下神经阻滞对小儿唇裂术后镇痛的临床效果.方法 选择95例确诊为唇裂并行手术治疗的患儿,随机双盲分为布比卡因组(B组)47例和布比卡因、吗啡复合组(BM组)48例.常规诱导气管插管后,B组取0.25％布比卡因2 ml;BM组取0.25％布比卡因2 ml+1μg/kg吗啡注射液；两组均行双侧眶下神经阻滞,每侧1 ml.观察两组术后FLACC疼痛评分及不良反应.结果 两组患儿术后3、6小时FLACC评分差异无显著性(P＞0.05),术后12、24小时差异有显著性(P＜0.05),术后48小时差异有极显著性(P＜0.01).B组总不良反应发生率为14.89％,BM组16.67％.结论 采用布比卡因、吗啡复合液行眶下神经阻滞对小儿唇裂术后具有良好的镇痛效果,且不良反应少,麻醉安全性高.
目的 觀察佈比卡因複閤嗎啡註射液應用于眶下神經阻滯對小兒脣裂術後鎮痛的臨床效果.方法 選擇95例確診為脣裂併行手術治療的患兒,隨機雙盲分為佈比卡因組(B組)47例和佈比卡因、嗎啡複閤組(BM組)48例.常規誘導氣管插管後,B組取0.25％佈比卡因2 ml;BM組取0.25％佈比卡因2 ml+1μg/kg嗎啡註射液；兩組均行雙側眶下神經阻滯,每側1 ml.觀察兩組術後FLACC疼痛評分及不良反應.結果 兩組患兒術後3、6小時FLACC評分差異無顯著性(P＞0.05),術後12、24小時差異有顯著性(P＜0.05),術後48小時差異有極顯著性(P＜0.01).B組總不良反應髮生率為14.89％,BM組16.67％.結論 採用佈比卡因、嗎啡複閤液行眶下神經阻滯對小兒脣裂術後具有良好的鎮痛效果,且不良反應少,痳醉安全性高.
목적 관찰포비잡인복합마배주사액응용우광하신경조체대소인진렬술후진통적림상효과.방법 선택95례학진위진렬병행수술치료적환인,수궤쌍맹분위포비잡인조(B조)47례화포비잡인、마배복합조(BM조)48례.상규유도기관삽관후,B조취0.25％포비잡인2 ml;BM조취0.25％포비잡인2 ml+1μg/kg마배주사액；량조균행쌍측광하신경조체,매측1 ml.관찰량조술후FLACC동통평분급불량반응.결과 량조환인술후3、6소시FLACC평분차이무현저성(P＞0.05),술후12、24소시차이유현저성(P＜0.05),술후48소시차이유겁현저성(P＜0.01).B조총불량반응발생솔위14.89％,BM조16.67％.결론 채용포비잡인、마배복합액행광하신경조체대소인진렬술후구유량호적진통효과,차불량반응소,마취안전성고.
Objective To study effects of bupivacaine and morphine combination with infraorbital nerve block on postoperative pain after cleft lip repair operation in paediatric patients.Methods 50 paediatric patients (ASA I) aged from 12 to 60 months undergoing cleft lip repair were randomly divided into two groups,25 cases for each group.After tracheal intubation,group B (using bupivacaine) received bilateral infraorbital nerve block with 1 ml of 0.25％ hupivacaine on each side and group BM (using bupivacaine and morphine combination) received 1 ml of 0.25％ bupivacaine along with 1 μ g/kg body weight morphine.Pain after recovery from anaesthesia was assessed postoperatively using the FLACC scale.Results Physical characteristics of the children studied had no significant differences.The duration of analgesia from the time of administration of block in group B was (20.2 ± 2.6) h compared to (36.8 ± 3.4) h in group BM (P＜0.01).Between two groups,the FLACC scale in group B was higher at 12,24 and 48 h postoperatively than those in group BM (P＜0.01).Conclusion Addition of morphine as an adjunct to local anaesthetic significantly prolongs the duration of postoperative analgesia without any adverse effects.
