国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
18期
1412-1417
,共6页
肺癌%甲状腺转录因子-1
肺癌%甲狀腺轉錄因子-1
폐암%갑상선전록인자-1
Lung cancer%Thyroid transcription factor-1
肺癌是目前全世界发病率最高的恶性肿瘤,其病死率也居于前列.因此,对肺癌的早期诊断及早期治疗对于降低肺癌患者的病死率以及改善患者生存质量至关重要.传统的肺癌诊断方法包括影像学检查以及病理学检查,现在仍然被临床所采用.但鉴于以上检查手段的敏感性、特异性、适用度等方面存在一定局限,近年来有关肺癌早期诊断、治疗及预后的分子标志物的研究愈来愈受到关注.本文就甲状腺转录因子-1的生物作用及其在肺癌诊断、治疗及预后方面的研究进展作一综述.
肺癌是目前全世界髮病率最高的噁性腫瘤,其病死率也居于前列.因此,對肺癌的早期診斷及早期治療對于降低肺癌患者的病死率以及改善患者生存質量至關重要.傳統的肺癌診斷方法包括影像學檢查以及病理學檢查,現在仍然被臨床所採用.但鑒于以上檢查手段的敏感性、特異性、適用度等方麵存在一定跼限,近年來有關肺癌早期診斷、治療及預後的分子標誌物的研究愈來愈受到關註.本文就甲狀腺轉錄因子-1的生物作用及其在肺癌診斷、治療及預後方麵的研究進展作一綜述.
폐암시목전전세계발병솔최고적악성종류,기병사솔야거우전렬.인차,대폐암적조기진단급조기치료대우강저폐암환자적병사솔이급개선환자생존질량지관중요.전통적폐암진단방법포괄영상학검사이급병이학검사,현재잉연피림상소채용.단감우이상검사수단적민감성、특이성、괄용도등방면존재일정국한,근년래유관폐암조기진단、치료급예후적분자표지물적연구유래유수도관주.본문취갑상선전록인자-1적생물작용급기재폐암진단、치료급예후방면적연구진전작일종술.
Lung cancer is the malignant carcinoma with the highest incidence and mortality all over the world.Consequently,early diagnosis and treatment may be very useful in reducing the mortality and improving the survival quality of patients.Traditional diagnostic methods of lung cancer still be used in chinic now,including imaging examinations and pathological examinations.Because of the limitation in sensitivity,specificity,and adaptability,the molecule markers for early diagnosis and treatment of lung cancer have received more and more attentions in recent years.In this article,the mechanism and application of thyroid transcription factor-1 in diagnosis,treatment,and evaluation of prognosis of lung cancer are reviewed.
