CAJ | 학술논문

竹红菌素类光动力药物由于其显著的光诱导抗肿瘤作用而受到日益广泛的关注，其高度的选择性和安全性等诸多特性和优点使之成为光动力药物研发领域一类备受瞩目的光敏剂体系。本文综述了近年来竹红菌素类光动力药物文献中关于其在各种疾病治疗研究特别足肿瘤治疗中的研究进展，以及其抗肿瘤机制基本原理和大量学者开展的竹红菌素结构修饰等研究工作成果，展望了竹红菌素类光动力药物在口腔颌面部肿瘤尤其是恶性肿瘤的治疗中的应用前景。
죽홍균소류광동력약물유우기현저적광유도항종류작용이수도일익엄범적관주，기고도적선택성화안전성등제다특성화우점사지성위광동력약물연발영역일류비수촉목적광민제체계。본문종술료근년래죽홍균소류광동력약물문헌중관우기재각충질병치료연구특별족종류치료중적연구진전，이급기항종류궤제기본원리화대량학자개전적죽홍균소결구수식등연구공작성과，전망료죽홍균소류광동력약물재구강합면부종류우기시악성종류적치료중적응용전경。
Hypocrellins have ginned considerable attention because of their＇light- induced antitumor. They been a new photosensitive drug system, which are greatestly focused on for their a great deal of specific properties and fortes such as highly selectivity and safety. In this paper, we summarized the development ofhypocrellin - based photosensitizers in various kinds of diseases treatment , especially in tufter treatment, the rudiment of antitumor and the structural mtlification by a lot of scholars. We also discussed the future application of hypocrellin - based photosensitizers in oromaxillo - facial region tumor , especi,dly in malignant tumor