CAJ | 학술논문

溶菌酶[Lysozyme（EC3.2.1.17）,LYZ]是机体先天免疫系统中一个重要的效应分子,参与机体多种免疫反应,在溶菌过程中形成一个水解体系,破坏和消除侵入动物体内的病原,从而实现机体的免疫防御。它可以有效抑制葡萄球菌、大肠杆菌等一系列病原菌,是重要的奶牛乳房炎抗性因子之一。本文综述了溶菌酶基因的研究进展,包括其结构与进化、变异及应用前景等。
용균매[Lysozyme（EC3.2.1.17）,LYZ]시궤체선천면역계통중일개중요적효응분자,삼여궤체다충면역반응,재용균과정중형성일개수해체계,파배화소제침입동물체내적병원,종이실현궤체적면역방어。타가이유효억제포도구균、대장간균등일계렬병원균,시중요적내우유방염항성인자지일。본문종술료용균매기인적연구진전,포괄기결구여진화、변이급응용전경등。
Lysozyme （LYZ, EC3. 2. 1. 17） is a key effective factor in body innate immune system, which participates in many kinds of body innate immune response. Lysozyme forms a hydrolyzed system when it plays a role in bacteriolysis. It damages and eliminates bacterial pathogens to realize body immune defense. Lysozyme is an important resistant factor of cow mastitis because of its effective inhibitory effect for many pathogenic bacteria such as Staphylococcus and Escherichia coli. This article reviews the advance of lysozyme gene features and its evolution, gene polymorphism and application prospect in animals.