CAJ | 학술논문

随着经济发展、人们生活方式改变，糖尿病已严重威胁人类健康。胰岛素抵抗是2型糖尿病发生的关键因素，从胰岛素合成后与胰岛素受体结合到实现生理效应的一系列过程中，都可能发生异常。运动疗法能够提高组织对胰岛素的敏感性，提高机体维持血糖稳定的激素调节能力。查阅了近年来国内外有关运动干预骨骼肌胰岛素功能的研究情况，分析了运动对骨骼肌胰岛素影响的主要因素，以及不同运动形式对骨骼肌胰岛素的影响。
수착경제발전、인문생활방식개변，당뇨병이엄중위협인류건강。이도소저항시2형당뇨병발생적관건인소，종이도소합성후여이도소수체결합도실현생리효응적일계렬과정중，도가능발생이상。운동요법능구제고조직대이도소적민감성，제고궤체유지혈당은정적격소조절능력。사열료근년래국내외유관운동간예골격기이도소공능적연구정황，분석료운동대골격기이도소영향적주요인소，이급불동운동형식대골격기이도소적영향。
Objective With the development of economy and change of life styles, diabetes mellitus seriously threatens the health of people. The key point of type 2 diabetes mellitusc to happen is insulin re- sistance, in which the abnormality will take place from the synthesis of insulin, the binding of insulin and its receptor, and physiological effect. Exercise can increase the insulin sensitivity of tissue and the hor- mone regulation ability of blood sugar stabilized by organism. This paper described the effects of exercise on the affinity of insulin receptor, influence of exercise on expression of skeletal muscle insulin receptor mRNA, and effects of exercise on insulin signal transduction. These could provide significant ideas in studying exercise-therapy of insulin resistance.