广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2012年
11期
84-86
,共3页
韦国兵%廖夫生%江国防
韋國兵%廖伕生%江國防
위국병%료부생%강국방
烯基膦酸酯%肟醚%乙氧羰基烯丙基取代肟醚%合成
烯基膦痠酯%肟醚%乙氧羰基烯丙基取代肟醚%閤成
희기련산지%우미%을양탄기희병기취대우미%합성
vinylphosphonate%oxime ethers%ethoxycarbonyl allyl substituted oxime ethers%synthesis
采用“一锅法”来研究这一反应。由酮肟1与氢化钠作用产生酮肟阴离子2，酮肟阴离子再与α-乙氧羰基乙烯基膦酸二乙酯3作用产生膦酸酯取代的碳负离子4，该碳负离子进一步与醛作用得到α-乙氧羰基烯丙基肟醚化合物，产率在73％～79％。
採用“一鍋法”來研究這一反應。由酮肟1與氫化鈉作用產生酮肟陰離子2，酮肟陰離子再與α-乙氧羰基乙烯基膦痠二乙酯3作用產生膦痠酯取代的碳負離子4，該碳負離子進一步與醛作用得到α-乙氧羰基烯丙基肟醚化閤物，產率在73％～79％。
채용“일과법”래연구저일반응。유동우1여경화납작용산생동우음리자2，동우음리자재여α-을양탄기을희기련산이을지3작용산생련산지취대적탄부리자4，해탄부리자진일보여철작용득도α-을양탄기희병기우미화합물，산솔재73％～79％。
Ketoxime anions 2, generated from the corresponding ketoximes 1 and sodium hydride, were reacted with α-ethoxycarbonylvinylphosphonate 3 to give the phosphoryl - stabilized carbanions 4 which were further reacted with alde- hydes affording α-ethoxycarbonyl allyl substituted oxime ethers in 73% -79% yields.
