CAJ | 학술논문

采用1：4配对的病例对照方法,选择行巨脾切除的患者60例,脾静脉最后分级离断原位巨脾切除术12例为改良组,常规原位巨脾切除术48例为对照组。改良组手术前后脾脏的长径(cm)分别为19.28依3.90、18.29依2.96,脾脏厚度(cm)分别为7.21依2.54、6.41依1.11,差异无统计学意义；输血量与出血量呈正相关(r=0.717,P<0.01)。与对照组比较,改良组出血量、输血量少,不良事件发生率低,差异有统计学意义(P<0.05),改良方法安全有效。
채용1：4배대적병례대조방법,선택행거비절제적환자60례,비정맥최후분급리단원위거비절제술12례위개량조,상규원위거비절제술48례위대조조。개량조수술전후비장적장경(cm)분별위19.28의3.90、18.29의2.96,비장후도(cm)분별위7.21의2.54、6.41의1.11,차이무통계학의의；수혈량여출혈량정정상관(r=0.717,P<0.01)。여대조조비교,개량조출혈량、수혈량소,불량사건발생솔저,차이유통계학의의(P<0.05),개량방법안전유효。
With a 1 : 4 matched case-control study design, 60 cases underwent orthotopic megasplenectomy were selected,among them,12 cases with splenic vein's secondary branch cutting in the last step were grouped to modi-fied group, and the other 48 cases underwent routine orthotopic megasplenectomy were grouped to control group. In modified group, before and after operation, there were no significant differences in the spleen length( cm) (19.28±3.90 vs 18.29±2.96, P>0.05) and thickness(cm)(7.21±2.54 vs 6.41±1.11,P>0.05),blood transfu-sion was positively correlated with bleeding(r=0.717, P<0.01). Compared with control group,the bleeding and transfusion volume and adverse event rate were significantly reduced in the modified group, suggesting that modified orthotopic megasplenectomy was safe and effective.