中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
CHINESE JOURNAL OF EVIDENCE-BASES CARDIOVASCULAR MEDICINE
2013年
6期
602-603
,共2页
心绞痛%抑郁%窦性心率震荡%动态心电图
心絞痛%抑鬱%竇性心率震盪%動態心電圖
심교통%억욱%두성심솔진탕%동태심전도
Angina%Depression%Sinus heart rate turbulence%Ambulatory electrocardiogram
目的：探讨抑郁对心绞痛型冠心病患者心率震荡（HRT）的影响。方法纳入2008年1月~2012年2月苏州市吴江第一人民医院心绞痛型冠心病患者78例，应用Zung抑郁自评量表（SDS）评定抑郁状况，其中不合并抑郁（SDS评价＜50）的40例患者作为对照组，合并抑郁患者38例作为观察组，并根据SDS评分将观察组进一步分为轻度抑郁组（50≤SDS评分＜60，n=14）、中度抑郁组（60≤SDS评分＜70，n=14）、重度抑郁组（SDS评分≥70，n=10）。所有入选患者均于入组时接受动态心电图检查，测量窦性HRT的参数，包括震荡起始（heart rate turbulance onset，TO）和震荡斜率（heart rate turbulence slope，TS），比较两组之间的差异。结果观察组TO较对照组显著升高[（2.16±1.06）%vs.（1.54±0.68）%，P=0.027]，TS较对照组患者显著降低[（2.33±1.95）ms/RRIvs.（4.47±3.89）ms/RRI， P=0.014]。观察组亚组分析显示，随着抑郁程度加重，TO逐渐升高而TS逐渐降低。结论抑郁可导致冠心病患者心率震荡明显减弱，抑郁程度越重，HRT减弱越明显。
目的：探討抑鬱對心絞痛型冠心病患者心率震盪（HRT）的影響。方法納入2008年1月~2012年2月囌州市吳江第一人民醫院心絞痛型冠心病患者78例，應用Zung抑鬱自評量錶（SDS）評定抑鬱狀況，其中不閤併抑鬱（SDS評價＜50）的40例患者作為對照組，閤併抑鬱患者38例作為觀察組，併根據SDS評分將觀察組進一步分為輕度抑鬱組（50≤SDS評分＜60，n=14）、中度抑鬱組（60≤SDS評分＜70，n=14）、重度抑鬱組（SDS評分≥70，n=10）。所有入選患者均于入組時接受動態心電圖檢查，測量竇性HRT的參數，包括震盪起始（heart rate turbulance onset，TO）和震盪斜率（heart rate turbulence slope，TS），比較兩組之間的差異。結果觀察組TO較對照組顯著升高[（2.16±1.06）%vs.（1.54±0.68）%，P=0.027]，TS較對照組患者顯著降低[（2.33±1.95）ms/RRIvs.（4.47±3.89）ms/RRI， P=0.014]。觀察組亞組分析顯示，隨著抑鬱程度加重，TO逐漸升高而TS逐漸降低。結論抑鬱可導緻冠心病患者心率震盪明顯減弱，抑鬱程度越重，HRT減弱越明顯。
목적：탐토억욱대심교통형관심병환자심솔진탕（HRT）적영향。방법납입2008년1월~2012년2월소주시오강제일인민의원심교통형관심병환자78례，응용Zung억욱자평량표（SDS）평정억욱상황，기중불합병억욱（SDS평개＜50）적40례환자작위대조조，합병억욱환자38례작위관찰조，병근거SDS평분장관찰조진일보분위경도억욱조（50≤SDS평분＜60，n=14）、중도억욱조（60≤SDS평분＜70，n=14）、중도억욱조（SDS평분≥70，n=10）。소유입선환자균우입조시접수동태심전도검사，측량두성HRT적삼수，포괄진탕기시（heart rate turbulance onset，TO）화진탕사솔（heart rate turbulence slope，TS），비교량조지간적차이。결과관찰조TO교대조조현저승고[（2.16±1.06）%vs.（1.54±0.68）%，P=0.027]，TS교대조조환자현저강저[（2.33±1.95）ms/RRIvs.（4.47±3.89）ms/RRI， P=0.014]。관찰조아조분석현시，수착억욱정도가중，TO축점승고이TS축점강저。결론억욱가도치관심병환자심솔진탕명현감약，억욱정도월중，HRT감약월명현。
Objective To investigate the influence of depression on heart rate turbulence (HRT) in the patients with angina coronary heart disease (CHD).Methods The patients (n=78) were chosen from Wujiang First People’s Hospital of Suzhou City from Jan. 2008 to Feb. 2012, and their depression status was assessed by using Zung Self-rating Depression Scale (SDS). The patients (n=40) without depression (SDS scores<50) were included into control group and those (n=38) with depression were included into observation group. The observation group was further divided into mild group (50≤SDS scores<60,n=14), moderate group (60≤SDS scores<70, n=14) and severe group (SDS scores≥70,n=10) according to SDS scores. All patients were given examinations of ambulatory electrocardiogram (ECG), and detection of sinus heart rate turbulence (HRT) parameters including heart rate turbulance onset (TO) and heart rate turbulence slope (TS) for comparing the difference between two groups. Results TO increased significantly [(2.16±1.06)%vs. (1.54±0.68)%,P=0.027] and TS decreased significantly [(2.33±1.95) ms/RRIvs. (4.47±3.89) ms/RRI,P=0.014] in observation group compared with control group. The analysis on sub-groups of observation group showed that TO increased gradually and TS decreased gradually as depression exacerbated.Conclusion Depression can attenuate HRT significantly, and HRT will more significant as depression exacerbates.
