安徽科技学院学报
安徽科技學院學報
안휘과기학원학보
JOURNAL OF ANHUI SCIENCE AND TECHNOLOGY UNIVERSITY
2012年
4期
1-3
,共3页
茯苓%利尿作用%兔
茯苓%利尿作用%兔
복령%이뇨작용%토
Poria cocos%Diuretic effect%Rabbits
观察茯苓水煎醇沉液对兔的利尿作用。取雄性家兔24只随机均分Ⅳ组,兔称重全身麻醉后固定于手术台上,沿尿道口将导尿管插入膀胱内收集尿液,连续记录1h内排尿量。Ⅰ-Ⅳ组分别按Og/kg、0.5g/kg、1.5g/kg、2.5g/kg剂量耳缘静脉注射茯苓水煎醇沉液。结果:静注茯苓水煎醇沉液1.5g/kg、2.5g/kg剂量组利尿作用明显(P〈0.01),其中2.5g/kg剂量组在给药10min内尿量出现高峰。表明茯苓对兔具有明显的利尿作用,并且存在一定程度的正向量效关系。
觀察茯苓水煎醇沉液對兔的利尿作用。取雄性傢兔24隻隨機均分Ⅳ組,兔稱重全身痳醉後固定于手術檯上,沿尿道口將導尿管插入膀胱內收集尿液,連續記錄1h內排尿量。Ⅰ-Ⅳ組分彆按Og/kg、0.5g/kg、1.5g/kg、2.5g/kg劑量耳緣靜脈註射茯苓水煎醇沉液。結果:靜註茯苓水煎醇沉液1.5g/kg、2.5g/kg劑量組利尿作用明顯(P〈0.01),其中2.5g/kg劑量組在給藥10min內尿量齣現高峰。錶明茯苓對兔具有明顯的利尿作用,併且存在一定程度的正嚮量效關繫。
관찰복령수전순침액대토적이뇨작용。취웅성가토24지수궤균분Ⅳ조,토칭중전신마취후고정우수술태상,연뇨도구장도뇨관삽입방광내수집뇨액,련속기록1h내배뇨량。Ⅰ-Ⅳ조분별안Og/kg、0.5g/kg、1.5g/kg、2.5g/kg제량이연정맥주사복령수전순침액。결과:정주복령수전순침액1.5g/kg、2.5g/kg제량조이뇨작용명현(P〈0.01),기중2.5g/kg제량조재급약10min내뇨량출현고봉。표명복령대토구유명현적이뇨작용,병차존재일정정도적정향량효관계。
To observe the diuretic effect of Poria cocos' decoction and alcohol deposit fluid in rabbits. 24 male rabbits were divided into 4 groups randomly. All rabbits are weighed and global anesthesia was under the operat- ing in turn, the catheter along the urethra into the bladder to collect urine, and continuous record of urine output was done within one hour. Ⅰ-Ⅳ groups were injected with Poria cocos' decoction and alcohol deposit fluid from ear vein and dose at 0g/kg 0.5g/kg, 1.5g/kg, 2.5g/kg respectively. Result: There were significant diu- retic effects (P 〈0.01 ) at intravenous 1.5g/kg, 2.5g/kg dose group, and urine output peak of 2.5g/kg dose group effect appeared within 10min. It is indicated that the Poria cocos has obvious diuretic effect in rabbits, and its did appear to positive correlation with dose to some extent.