CAJ | 학술논문

为了建立盐酸氟桂利嗪生产过程中的快速分析方法,采用紫外-分光光度法和高效液相色谱法对盐酸氟桂利嗪进行测定。对比结果表明,以盐酸为溶剂,选择253 nm为测定波长,在盐酸氟桂利嗪为7.488～17.472μg.mL-1的浓度范围内,紫外-分光光度法与高效液相色谱法具有很好的可靠性,可以作为生产过程质量控制的快速测定方法。
위료건립염산불계리진생산과정중적쾌속분석방법,채용자외-분광광도법화고효액상색보법대염산불계리진진행측정。대비결과표명,이염산위용제,선택253 nm위측정파장,재염산불계리진위7.488～17.472μg.mL-1적농도범위내,자외-분광광도법여고효액상색보법구유흔호적가고성,가이작위생산과정질량공제적쾌속측정방법。
In order to establish an accurate and speedy detection method for manufacture process of the flunarizine hydrochloride capsules,a spectrophotometry method was studied by comparing with HPLC method.The linear rang was 7.488～17.472 μg·mL-1 when hydrochloric acid was used as solvent,and 253 nm as detection wavelength.The results showed that the spectrophotometry method had high accurate same as HPLC,and could be used as speedy detection method.