CAJ | 학술논문

目的：了解大理地区志贺菌的血清型分布及对12种常用抗生素的耐药性。方法：通过分离培养和鉴定得到68株志贺菌,血清学鉴定其血清型,K-B法检测其对12种抗生素的敏感性。结果：血清学鉴定显示68株志贺菌中福氏志贺菌41株,宋内氏志贺菌25株,鲍氏志贺菌2株。志贺菌对萘啶酸耐药率最高,对复方磺胺甲噁唑和氨苄西林耐药率较高;对头孢曲松和头孢噻肟较敏感,对喹诺酮类显示出不同程度的耐药。结论：大理地区以福氏志贺菌感染为主。在志贺菌治疗中可首选头孢曲松和头孢噻肟。
목적：료해대리지구지하균적혈청형분포급대12충상용항생소적내약성。방법：통과분리배양화감정득도68주지하균,혈청학감정기혈청형,K-B법검측기대12충항생소적민감성。결과：혈청학감정현시68주지하균중복씨지하균41주,송내씨지하균25주,포씨지하균2주。지하균대내정산내약솔최고,대복방광알갑오서화안변서림내약솔교고;대두포곡송화두포새우교민감,대규낙동류현시출불동정도적내약。결론：대리지구이복씨지하균감염위주。재지하균치료중가수선두포곡송화두포새우。
Objective： To investigate the serotype distribution of Shigellae in Dali and evaluate the resistance of Shigellae to 12 common used drugs. Methods： Serotypes of 68 isolated and identified strains of Shigellae were measured. K-B test was applied to define the drug-resistance of Shigellae to 12 different drugs. Results： Among 68 strains examined, 41 were Shigella Flexner, 25 were Shigella sonnei and 2 were Shigella boydii identified by serotype. Shigellae showed the highest drug resistance to nalidixic acid, with followed sulfalene and nalidixic and varying extents of drug resistance to quinolones; Shigellae was sensitive to ceftriaxone and cefotaxime. Conclusion： These results suggest that Shigella Flexner is the main infection strains in Dali and ceftriaxone and cefotaxime should be preferred in the treatment with Shigellae.