大理学院学报：综合版
大理學院學報：綜閤版
대이학원학보：종합판
Journal of Dali University
2012年
6期
5-11
,共7页
高鹏飞%刘卫红%李凤贤%李辉%杜一民%刘蜻蜻%巫秀美%赵昱%刘光明
高鵬飛%劉衛紅%李鳳賢%李輝%杜一民%劉蜻蜻%巫秀美%趙昱%劉光明
고붕비%류위홍%리봉현%리휘%두일민%류청청%무수미%조욱%류광명
天然药物%有效部位%单体活性成分%肝纤维化%治疗肝纤维化%新药研发
天然藥物%有效部位%單體活性成分%肝纖維化%治療肝纖維化%新藥研髮
천연약물%유효부위%단체활성성분%간섬유화%치료간섬유화%신약연발
natural drugs%active fractions%active monomer%liver fibrosis%anti-liver fibrosis%new drug research and development
目的：综述近年来用于治疗肝纤维化天然药物的有效部位及单体活性成分的研究进展。方法：对34种天然药物的生物碱类、总黄酮和总酚酸类、单体酚酸类、萜类及其苷和甾醇类、木脂素类、氨基酸/多肽和杂环类、多糖类、香豆素类进行分析。结果：已报道的34种天然药物对肝纤维化均具有一定的治疗效果。结论：对未来治疗肝纤维化的新药研发方向进行展望。
目的：綜述近年來用于治療肝纖維化天然藥物的有效部位及單體活性成分的研究進展。方法：對34種天然藥物的生物堿類、總黃酮和總酚痠類、單體酚痠類、萜類及其苷和甾醇類、木脂素類、氨基痠/多肽和雜環類、多糖類、香豆素類進行分析。結果：已報道的34種天然藥物對肝纖維化均具有一定的治療效果。結論：對未來治療肝纖維化的新藥研髮方嚮進行展望。
목적：종술근년래용우치료간섬유화천연약물적유효부위급단체활성성분적연구진전。방법：대34충천연약물적생물감류、총황동화총분산류、단체분산류、첩류급기감화치순류、목지소류、안기산/다태화잡배류、다당류、향두소류진행분석。결과：이보도적34충천연약물대간섬유화균구유일정적치료효과。결론：대미래치료간섬유화적신약연발방향진행전망。
Objective： To review the recent research progress domestic and abroad of the utilization of natural drugs for the treatment of liver fibrosis. Methods：Thirty-four reported natural drugs were summarized and classified into alkaloids, total flavonoids and total phenolics, single phenolics, terpenoids and its glycosides and steroids, lignanoids, amino acids and heterocyclic, polypeptides/ glycopeptides and coumarins. Results： Thirty-four reported natural drugs all have certain effect for the treatment of liver fibrosis. Conclusion： The prospect of the research and development of the new natural drugs against liver fibrosis were discussed.
