CAJ | 학술논문

目的：掌握绍兴市肺结核患者耐药情况，为预防控制肺结核提供依据。方法对2010-2013年6月在绍兴市结核病定点医院就诊的涂阳肺结核患者痰标本分离株进行菌型鉴定，用药敏罗氏培养基进行药物敏感性试验，分析肺结核患者的耐药情况。结果在607份痰培养阳性标本中，总耐药率为20.26％，耐多药（MDR-TB）率12.85％，耐药率由高到低依次为INH、RFP、SM和EMB；初治总耐药率13.09％，耐多药率5.73％；复治总耐药率为50.00％，耐多药率42.37％。结论绍兴市结核分枝杆菌的总耐药率与全国平均水平相当，但复治病例耐多药率仍较高。
목적：장악소흥시폐결핵환자내약정황，위예방공제폐결핵제공의거。방법대2010-2013년6월재소흥시결핵병정점의원취진적도양폐결핵환자담표본분리주진행균형감정，용약민라씨배양기진행약물민감성시험，분석폐결핵환자적내약정황。결과재607빈담배양양성표본중，총내약솔위20.26％，내다약（MDR-TB）솔12.85％，내약솔유고도저의차위INH、RFP、SM화EMB；초치총내약솔13.09％，내다약솔5.73％；복치총내약솔위50.00％，내다약솔42.37％。결론소흥시결핵분지간균적총내약솔여전국평균수평상당，단복치병례내다약솔잉교고。
Objective To analyze the characteristics of drug resistance in tuberculosis patients in Shaoxing and provide scientific basis for prevention and control of tuberculosis.Methods All the sputum smear -positive specimens from tuberculosis patients in Shaoxing tuberculosis designated hospitals from 2010 to June 2013 had been done by susceptibility test using susceptibility Jensen medium.The situation of drug resistance in patients with pulmonary tuberculosis was analysed.Results In the 607 sputum culture -positive cases,the total resistance rate was 20.26%;the multi -drug resistance rate was 12.85%.The resistance rate in descending order was INH,RFP,SM and EMB.In new cases,the total resistance rate was 13.09%,and the multi-drug resistance rate was 5.73%;in retreated cases,the total resistance rate was 50.00%,and the multi-drug resistance rate was 42.37%.Conclusion In Shaoxing City,the total resistance rate of tuberculosis is consistent with the national average level,but the epidemic of MDR-TB is still very serious.