宁夏农林科技
寧夏農林科技
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NINGXIA JOURNAL OF AGRICULTURE AND FORESTRY SCIENCE AND TECHNOLOGY
2012年
8期
139-140
,共2页
张贵源%龚莉莉%余跃生%王恒%陆玉炯%杨再昌
張貴源%龔莉莉%餘躍生%王恆%陸玉炯%楊再昌
장귀원%공리리%여약생%왕항%륙옥형%양재창
黑骨藤%PC12细胞%抗氧化
黑骨籐%PC12細胞%抗氧化
흑골등%PC12세포%항양화
Periploca forrestii Schltr.%PC12 cells%Anti-oxidative effect
[目的]研究黑骨藤提取物对H2O2诱导的PC12氧化损伤的保护作用。[方法]使用H2O2氧化压力诱导PC12出现氧化损伤,检测黑骨藤乙醇提取物对PC12细胞的保护作用。[结果]与模型对照组相比,黑骨藤乙醇提取物浓度在16~128μg/mL时,能显著提高PC12细胞的存活率,呈典型的量效关系。[结论]黑骨藤乙醇提取物具有抗氧化损伤作用。
[目的]研究黑骨籐提取物對H2O2誘導的PC12氧化損傷的保護作用。[方法]使用H2O2氧化壓力誘導PC12齣現氧化損傷,檢測黑骨籐乙醇提取物對PC12細胞的保護作用。[結果]與模型對照組相比,黑骨籐乙醇提取物濃度在16~128μg/mL時,能顯著提高PC12細胞的存活率,呈典型的量效關繫。[結論]黑骨籐乙醇提取物具有抗氧化損傷作用。
[목적]연구흑골등제취물대H2O2유도적PC12양화손상적보호작용。[방법]사용H2O2양화압력유도PC12출현양화손상,검측흑골등을순제취물대PC12세포적보호작용。[결과]여모형대조조상비,흑골등을순제취물농도재16~128μg/mL시,능현저제고PC12세포적존활솔,정전형적량효관계。[결론]흑골등을순제취물구유항양화손상작용。
[Objective] The aim was to study the protective effects of Periploca forrestii Schltr.root extract against cytotoxicity induced by hydrogen peroxide in PC12 cells.[Method] The model of PC12 cells toxicity induced by hydrogen peroxide was established and the protective effects of Periploca forrestii Schltr.root extract on PC12 cells were detected.[Result] Compared to negative control,Periploca forrestii Schltr.root extract could protect PC12 cells at concentration ranges of 16-128 ug/mL at a dose-response manner.[Conclusion] Periploca forrestii Schltr.root extract showed anti-oxidative effect on PC12 cells.
