CAJ | 학술논문

研究光动力疗法（photodynamic therapy,PDT）治疗肿瘤的机制.方法：建立裸鼠胰腺癌模型,以血卟啉衍生物作为光敏剂,测定PDT治疗后,肿瘤组织内脂质过氧化产物丙二醛（MDA）的含量,并采用免疫组化LSAB法,对肿瘤区血管损伤状况进行研究.
연구광동력요법（photodynamic therapy,PDT）치료종류적궤제.방법：건립라서이선암모형,이혈계람연생물작위광민제,측정PDT치료후,종류조직내지질과양화산물병이철（MDA）적함량,병채용면역조화LSAB법,대종류구혈관손상상황진행연구.
To study the mechanism of photodynamic the nude mice animal model of pancreatic cancer , the photosens After the therapy the level of MDA in different groups was rapy （PDT） to neoplasm. Methods ： developing the itizers HPD was given by the intraperitoneal injection, analysed and factor - Ⅷwas used in the immunohisto- chemical staining to study the vessel change. Results; The level of MDA in the PDT group was higher than that of the controls , immunohistochemical staining showed PDT can make injury to vessel endothelial cell and destruct vessel structure. PDT can induce injuries of neoplasm , oxidation and vascular injury is important way to exert function.