CAJ | 학술논문

目的：观察咪唑斯汀联合中药玉屏风散治疗慢性荨麻疹的临床疗效及安全性。方法将120例慢性荨麻疹患者采用随机数字表分组法分为2组，试验组62例口服咪唑斯汀10 mg/d，联合玉屏风散1剂/天，分2次口服；对照组58例，口服咪唑斯汀，用法、用量同试验组。2组均连续用药治疗4周，并分别在1周、2周、4周依据治疗前、后患者的临床症状、体征下降指数进行疗效评估。结果试验组有效率为91.93%，对照组为70.69%，2组比较差异有统计学意义（P<0.01）。结论咪唑斯汀联合玉屏风治疗慢性荨麻疹疗效好，毒副作用小，治愈率高，复发率低。
목적：관찰미서사정연합중약옥병풍산치료만성담마진적림상료효급안전성。방법장120례만성담마진환자채용수궤수자표분조법분위2조，시험조62례구복미서사정10 mg/d，연합옥병풍산1제/천，분2차구복；대조조58례，구복미서사정，용법、용량동시험조。2조균련속용약치료4주，병분별재1주、2주、4주의거치료전、후환자적림상증상、체정하강지수진행료효평고。결과시험조유효솔위91.93%，대조조위70.69%，2조비교차이유통계학의의（P<0.01）。결론미서사정연합옥병풍치료만성담마진료효호，독부작용소，치유솔고，복발솔저。
Objective To observe the clinical curative effects and security of mizolastine combined with traditional Chinese medicine(Yupingfengsan) in the treatment of chronic urticaria. Methods 120 patients of chronic urticaria were divided into 2 groups randomly. The experimental group had 62 patients while the control group had 58 patients. The patients in experimental group took mizolastine 10 mg/d and Yupingfengsan 1 dose/d twice a day. The control group took mizolastine 10mg/d only. The two groups were treated continuously for four weeks together. The clinical curative effects were appraised according to the clinical symptoms and physical decline index before and after the treatment at 1st, 2nd week and 4th week. Results The effective rates were 91.93%and 70.69%respectively in the experimental group and the controls. There was a signiifcant difference between the two groups(P<0.01). Conclusion Mizolastine combined with traditional Chinese medicine(Yupingfensan) is quite effective in the treatment of chronic urticaria, with less side effects, high cure rate and low recurrence.